Formation of an FGF-2-Apatite Composite Layer on Ethylene-Vinyl Alcohol Copolymer

Kenkichi Sasaki; Ayako Oyane; Koji Hyodo; Atsuo Ito; Yu Sogo; Masanobu Kamitakahara; Koji Ioku

doi:10.4028/www.scientific.net/KEM.361-363.455

Paper Titles

Macro/Microporous Biphasic Calcium Phosphate Cylinders and Resorbable Collagen Membranes for Guided Bone Growth
p.439

Porous Hydroxyapatite Surface-Modified by Polypyrrole-Heparin Conducting Polymer
p.443

Sol-Gel Synthesis and In Vitro Cell Compatibility Analysis of Silicate-Containing Biodegradable Hybrid Gels
p.447

Modified Poly-ε-Caprolactone (PCL) with Phosphorous Containing Compounds for Biomineralization
p.451

Formation of an FGF-2-Apatite Composite Layer on Ethylene-Vinyl Alcohol Copolymer
p.455

Apatite Formation on α-Tricalcium Phosphate/Poly(D,L-Lactide-Co-Glycolide) Nanocomposite
p.459

Preparation and Evaluation of Nano-Hydroxyapatite/β-Tricalcium Phosphate/Chitosan Composite Scaffolds for Bone Tissue Engineering
p.463

Heavy Metals Immobilization by Hydroxyapatite-Alginate Composite in Simulated Gastric Fluid
p.467

A Review of Two Animal Studies Dealing with Biological Responses to Glass-Fibre-Reinforced Composite Implants in Critical Size Calvarial Bone Defects in Rabbits
p.471

HomeKey Engineering MaterialsKey Engineering Materials Vols. 361-363Formation of an FGF-2-Apatite Composite Layer on...

Formation of an FGF-2-Apatite Composite Layer on Ethylene-Vinyl Alcohol Copolymer

Abstract:

A composite layer of fibroblast growth factor-2 (FGF-2) and low-crystalline apatite was formed on an ethylene-vinyl alcohol copolymer specimen using two types of aqueous calcium phosphate solutions supplemented with 10 !g·mL-1 FGF-2; one is a CP solution that is prepared by dissolving chemical reagents into ultrapure water and the other is an RKB solution that can be prepared by mixing clinically approved infusion fluids. In both solutions, a sufficient amount of FGF-2 for new skin tissue formation (1 !g·cm-2) was immobilized on the specimen surface.