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Three Dimensional Macroporous Calcium Phosphate Scaffolds for Bone Tissue Engineering

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Abstract:

Calcium phosphate ceramics are widely used as bone substitutes since they are biocompatible and bioactive. Having a chemical composition close to natural bone, calcium phosphate ceramics are promising bone substitute materials in orthopaedics, maxillofacial surgery and dentistry. Hydroxyapatite (HA) and tricalcium phosphate (TCP) are the most commonly used calcium phosphates, because their calcium/phosphorus (Ca/P) ratios are close to that of natural bone and they are relatively stable in physiological environment. HA is a major constituent of bone materials and is resorbed after a long time of residence in the body. In this work, highly porous hydroxyapatite scaffolds were produced by polymer replication method and their properties evaluated by Scanning Electron Microscopy (SEM) and micro computerized tomography ()-CT).

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Periodical:

Key Engineering Materials (Volumes 361-363)

Pages:

947-950

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.361-363.947

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Online since:

November 2007

Authors:

S. Teixeira, S.M. Oliveira, M.P. Ferraz, F.J. Monteiro

Keywords:

Calcium Phosphate, Micro Computed Tomography (μ-CT), Porous, Scaffold

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© 2008 Trans Tech Publications Ltd. All Rights Reserved

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References

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