Paper Titles
Exchange Reactions at Calcium Phosphates Surface and Applications to Biomaterials
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Preparation of Spherical Porous Granules Composed of Rod-Shaped Hydroxyapatite and Evaluation of their Protein Adsorption Properties
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Surface Structure, Hydration and Cationic Sites of Nanohydroxyapatite
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Influence of Two-Step Sintering Variables on Phase Stability of Hydrothermally Prepared HAp Nano Powders
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Internal Diffusion of Micro/Nanoparticles Inside Body
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The Structure and Properties of Electroceramics for Bone Graft Substitution
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Variations in the Compression Strength of Cylindrical Samples Made of Dense Hydroxyapatite
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The Differences between the Direct and Sol-Gel Syntheses of Silicon-Contained Calcium Phosphates
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Montmorillonite-Added Calcium Phosphate Bioceramic Foams
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Internal Diffusion of Micro/Nanoparticles Inside Body

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Abstract:

Both biochemical cell functional test and animal implantation test were done to investigate the reaction to fine particles. Particles cause nonspecifically phagocytosis to cells and inflammation to tissue for the size below 10m. With the size below 50nm particles may invade into the internal body through the respiratory or digestive system and diffuse inside body. Ti mapping by XSAM after the compulsory exposure test to the respiratory system showed the internal diffusion of 30nm TiO2 particles. They diffused with time course to lung, liver and spleen after injection from caudal vein. Nanoparticles might be the objects whose existence has not been assumed by the biophylactic system.

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Periodical:

Key Engineering Materials (Volumes 361-363)

Pages:

95-98

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.361-363.95

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Online since:

November 2007

Authors:

Fumio Watari, Shigeaki Abe, Kazuchika Tamura, Motohiro Uo, Atsuro Yokoyama, Yasunori Totsuka

Keywords:

Biocompatibility, Cytokine, Internal Diffusion, Macrophage, Nanoparticle, Nanotoxicology, Neutrophils, Phagocytosis, Superoxide, Titanium (Ti)

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© 2008 Trans Tech Publications Ltd. All Rights Reserved

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