Paper Titles
Study on Physicochemical Properties of the Carbonated Hydroxyapatite Bone Cement
p.1545
Mechanical Properties of Macroporous Biphasic Calcium Phosphate Bioceramics Fabricated Using a Porogen
p.1549
Gelcasting of Mechanochemically Synthesized Hydroxyapatite
p.1555
Synthesis of Calcium Phosphate/Gypsum Composite Powders
p.1559
Processing of Calcium Phosphate Porous Materials by 'Self-Setting'
p.1563
Setting Behavior of Fast-Setting Calcium Phosphate Cement with Mineral Phase of Bone
p.1567
Synthesis of Apatite Ceramics with Bimodal Pore Structure Using Mechanochemically Prepared Fine Apatite Powder
p.1571
Formation of Bone-Like Apatite of Bioceramics Modified by Cold Plasma in SBF and Mechanism of Active Modification
p.1575
Apatite Formation on Porous TCP In Vitro: A Comparative Study between Static and Dynamic RSBF Systems
p.1581

Processing of Calcium Phosphate Porous Materials by 'Self-Setting'

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Abstract:

Macroporous biomaterials based on a-tricalcium phosphate (a-TCP) bone cement with porous structures suitable for implantation purposes were prepared in the present work. According to the reversible swelling/deswelling behavior of gelatin at a single temperature or pH, a “self-setting” method that uses gelatin granules as pore formers was developed to process the porous microstructure. By mixing gelatin powder and bone cement powder (BCP), and adding water (1% solution of NaH2PO4×HO) to form pastes which set within 15 to 30 min, this setted cement was then immerged in deionized water of temperature 25°C or 32°C for hydration. During the hydration, the pH of deionized water after cement pastes were introduced at 32°C changed from 8.6 to 7.2 which caused by the transformation of a-TCP to hydroxyapatite (HA). Meanwhile, gelatin particles will swell by water uptake to form large size spheres in cementmatrix. This swelling behavior is sensitive to the variation of pH value. After hydration for 4 day, a body containing gelatin gel spheres was obtained. Then heating the deionized water to temperature 50°C, gelatin spheres in cement matrix were solved and porous microstructure composed of larger pore sizes corresponding approximately to the average size of the swelling gelatin granules was obtained. The porous bodies by this technique were found to have tractable and interconnected porosity in the range of 60~84%, with typical pore sizes ranging from 100~300 microns. This new processing technique can be used in the manufacture of unsintered biomaterials.

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Periodical:

Key Engineering Materials (Volumes 280-283)

Pages:

1563-1566

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.280-283.1563

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Online since:

February 2007

Authors:

Shu Cai, Yan Wei Wang, Kang De Yao

Keywords:

Calcium Phosphate, Gelatin Swelling, Porous Material, Self-Setting

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© 2005 Trans Tech Publications Ltd. All Rights Reserved

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