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In Vitro Behavior of Yttrium Silica Sol-Gel Microspheres

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Abstract:

Biodegradable silica microspheres containing neutron activable yttrium cations were investigated as a potential material for in situ radiotherapy of cancers. The sol-gel method used for preparing the microspheres allows obtaining at relative low temperatures materials of high purity and homogeneity, with controlled rate of biodegradability. The influence of yttrium on the biodegradability of the silica microspheres was studied in a simulated body fluid (SBF). The chemical durability of the microspheres was investigated under in vitro conditions and the concentration of yttrium released from the microspheres was determined.

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Bioceramics 17 View Preview

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Periodical:

Key Engineering Materials (Volumes 284-286)

Pages:

411-414

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.284-286.411

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Online since:

April 2005

Authors:

D. Cacaina, Reeta Viitala, Mika Jokinen, Heimo O. Ylänen, Mikko Hupa, S. Simon

Keywords:

Bioactive Glass, Release Behaviour, Simulated Body Fluid (SBF), Sol-Gel (SG), Yttrium

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© 2005 Trans Tech Publications Ltd. All Rights Reserved

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