Biocompatibility of Polyethylene Doped with Oxycellulose

Regina Mikulíková; Kateřina Kolářová; Lucie Bačáková; Václav Švorčík

doi:10.4028/www.scientific.net/MSF.482.251

Paper Titles

Influence of Material State at a Crack Tip on the Process of Fatigue Striations Formation for Al-Based Alloys
p.235

Grain Size Estimation in Anisotropic Materials
p.239

Application of Silicon for a Protection of Titanium against High-Temperature Oxidation
p.243

Biocompatibility of Carbon Layer on Polymer
p.247

Biocompatibility of Polyethylene Doped with Oxycellulose
p.251

Strain Heterogeneity and Damage Localization in Nodular Cast Iron Microstructures
p.255

Textural Fractography of Fatigue Failures under Variable Cycle Loading
p.259

Analysis of Fracture Morphology and Local Loading Modes in Torsional Fatigue
p.263

Effect of Structure on Creep Behaviour of Superalloy Single Crystals
p.267

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Biocompatibility of Polyethylene Doped with Oxycellulose

Abstract:

Physical and chemical properties of polyethylene (PE) films doped with calcium salt of oxycellulose (Ca-oxy) and its interaction with cells in culture conditions were studied. The samples with various concentrations of Ca-oxy (0-20 %) were prepared. Samples were tested by goniometer measurements, X-ray diffraction, FTIR spectroscopy and SEM. Sample weight changes during boil sterilization and adhesion and proliferation of tissue cells (3T3 mouse fibroblasts) were studied. It was found that wetting angle of the doped films decreased with increasing Ca-oxy concentration to up to 10% and then increased again. Both film surfaces had different amount of crystalline phase, thereby different surface roughness. Due to a smaller surface roughness, cell growth was much better on the inner surface of the film than on the outer one. Cells adhered better to samples with 1% of Ca-oxy and with a higher content of oxycellulose over 7%. Cell proliferation was the best on samples with 1-5% Ca-oxy. Samples were polished to modify their surface roughness. Polishing increased cell proliferation especially on samples with a lower Ca-oxy concentration (1-5%).