Effect of OH Content on the Bioactivity of Sol-Gel Derived Glass Foam Scaffolds

Julian R. Jones; T.F. Kemp; M.E. Smith

doi:10.4028/www.scientific.net/KEM.309-311.1031

Paper Titles

Posterolateral Lumbar Fusion by Tissue Engineered Bone
p.1013

Organ Regeneration in Porous Hydoroxyapatite
p.1017

Porous Bioceramics (Open Cell Foams) Expanded in Vacuum
p.1023

Hydroxyapatite Formation on Cellular Alumina Coated with Bioactive Glasses
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Effect of OH Content on the Bioactivity of Sol-Gel Derived Glass Foam Scaffolds
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Evaluation of Biocompatibility for Porous Bioactive Glass Scaffolds
p.1035

Porous Composite with Tunnel-like Interconnecting Pores of Hydroxyapatite with Magnetite Particles
p.1039

Electrovector Effect of Polarized Porous Hydroxyapatite Ceramics
p.1043

Effect of Cooling Rate and Particle Size on Compressive Strength of Macroporous Hydroxyapatite
p.1047

HomeKey Engineering MaterialsKey Engineering Materials Vols. 309-311Effect of OH Content on the Bioactivity of Sol-Gel...

Effect of OH Content on the Bioactivity of Sol-Gel Derived Glass Foam Scaffolds

Abstract:

Bioactive glass scaffolds have been developed with interconnected macropore networks, with pore diameters in excess of 500µm and apertures in excess of 100µm, by foaming sol-gel derived bioactive glasses. Bioactive glasses bond to bone by forming a hydroxycarbonate apatite (HCA) layer on their surface on contact with body fluid, which is similar to the composition of the apatite in bone. The aim of this work was to investigate the how changing the atomic structure of the glass affects HCA layer formation. Scaffolds were synthesised at 3 sintering temperatures and were characterised using 29Si and proton MAS-NMR, from which the silica network connectivity and Si-OH groups were quantified. The rate of HCA layer formation decreased as the number of Si-OH groups decreased, confirming the role of Si-OH groups in HCA layer formation.