Biological Evaluation of a Laminin–Apatite–Polymer Composite for Use in Skin Terminals

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Abstract:

An ethylene-vinyl alcohol copolymer (EVOH) film with a laminin–apatite composite layer on its surface showed improved adhesion and compatibility to living epithelial tissue compared to untreated EVOH film. This result can be attributed to the good biocompatibility of apatite and the cell-adhesion activity of the laminin on the EVOH surface. This composite material, consisting of laminin, apatite, and EVOH, is considered a promising material for skin terminals to prevent epidermal downgrowth.

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Key Engineering Materials (Volumes 309-311)

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1181-1184

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May 2006

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© 2006 Trans Tech Publications Ltd. All Rights Reserved

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DOI: 10.1002/jbm.b.10002

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