Paper Titles
Inherent Luminescence of Annealed Biomimetic Apatites
p.655
Apatite Pattern Formation by Electrophoretic Deposition Transcribing Resist Pattern
p.659
Development of Apatite Micropattern Test Specimen for Cell Operation
p.663
Deposition of Bone-like Apatite Layers on the Surface of Poly(L-Lactic Acid) Using Immobilized Urease
p.667
Apatite Deposition on Polypeptides Derived from Plants in a Solution Mimicking Body Fluid
p.671
Preparation of Apatite-Polyglutamic Acid Hybrid Through Biomimetic Process
p.675
Apatite Coating on Ti Surface Using Alternate Soaking Process
p.679
High Resolution Microscopy of Nanocrystalline Hydroxyapatite Coatings
p.685
Surface Topography Characterization of Apatite Formation on Bioactive Glass Modified Dental Ceramics Using Confocal Laser Scanning CLSM) and Environmental Scanning Electron Microscopy (ESEM)
p.689

Apatite Deposition on Polypeptides Derived from Plants in a Solution Mimicking Body Fluid

Article Preview

Abstract:

Organic-inorganic hybrids composed of organic polymer and apatite is quite attractive as novel bone-repairing materials since it has mechanical performance analogous to those of natural bone as well as bone-bonding ability, i.e. bioactivity. To fabricate such an apatite-polymer hybrid, biomimetic process has been recently paid much attention. In this process, bone-like apatite is deposited on the surfaces of organic substrates in simulated body fluid (SBF, Kokubo solution) having ion concentrations analogous to those of human extracellular fluid or more concentrated solutions. Previous studies showed that the apatite deposition is triggered by a catalytic effect of carboxyl groups (COOH) on the surfaces of the organic substrates. In this study, we examined apatite deposition on natural polypeptides derived from crops in a biomimetic solution. We selected gluten derived from wheat and zein derived from corn. Both of gluten and zein formed bone-like apatite on their surfaces in a solution that has inorganic ion concentrations 1.5 times those of simulated body fluid, when they were treated with 1 mol/L calcium chloride solution. High content of acidic amino acids such as glutamic acid and aspartic acid in gluten and zein would give large amount of carboxyl groups effective for the apatite nucleation.

You might also be interested in these eBooks
Bioceramics 18 View Preview

Info:

Periodical:

Key Engineering Materials (Volumes 309-311)

Pages:

671-674

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.309-311.671

Citation:

Cite this paper

Online since:

May 2006

Authors:

Toshiki Miyazaki, Chikara Ohtsuki, Shinichi Ogata, Masahiro Ashizuka

Keywords:

Apatite, Biomimetic Process, Gluten, Polypeptide, Zein

Export:

RIS, BibTeX

Price:

Permissions CCC:

Request Permissions

Permissions PLS:

Request Permissions

Сopyright:

© 2006 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

References

[1] M. Tanahashi, T. Yao, T. Kokubo, M. Minoda, T. Miyamto, T. Nakamura and T. Yamamuro: J. Am. Ceram. Soc. Vol. 77 (1994), p.2805.

Google Scholar

[2] P. Li, C. Ohtsuki, T. Kokubo, K. Nakanishi, N. Soga and K. deGroot: J. Biomed. Mater. Res. Vol. 28 (1994), p.7.

Google Scholar

[3] M. Uchida, H. -M. Kim, T. Kokubo, F. Miyaji and T. Nakamura: J. Am. Ceram. Soc. Vol. 84 (2001), p. (2041).

Google Scholar

[4] T. Miyazaki, H. -M. Kim, T. Kokubo, H. Kato and T. Nakamura: J. Sol-gel Sci. Tech. Vol. 21 (2001), p.83.

Google Scholar

[5] T. Miyazaki, H. -M. Kim, T. Kokubo, C. Ohtsuki and T. Nakamura: J. Ceram. Soc. Japan Vol. 109 (2001), p.934.

Google Scholar

[6] M. Tanahashi and T. Matsuda: J. Biomed. Mater. Res. Vol. 34 (1997), p.305.

Google Scholar

[7] B.S. Kayserilioglu, W.M. Stevels, W.J. Mulder and N. Akkas: Starch Vol. 53 (2001), p.381.

Google Scholar

[8] G.E. Inglett (ed. ): Wheat: Production and Utilization (Avi Pub Co., CT 1974).

Google Scholar

[9] R. Shukla and M. Cheryan: Industrial Crops and Products Vol. 13 (2001), p.171.

Google Scholar