Synthesis and Characterization of Mesostructured Silicas and Gold Frameworks as Active Matrices for Biomolecule Encapsulation

Article Preview

Abstract:

Interfacing of biomolecules to inorganic frameworks is essential for fabricating robust, functionally integrated biocomposites that may prove useful in a wide range of technologies including biocatalysis, biosensors or protein-based devices. Our work is directed at developing means to integrate biomolecules into mesostructured inorganics. These frameworks serve to both improve the mechanical stability of the proteins and to facilitate communication with them. Toward that end, we have synthesized and characterized mesoporous silicas and conductive metallic frameworks and have examined the encapsulation of both soluble (cytochrome c) and membrane proteins (bacteriorhodpsin) within them.

You might also be interested in these eBooks

Info:

Periodical:

Pages:

30-37

Citation:

Online since:

October 2006

Export:

Price:

Permissions CCC:

Permissions PLS:

Сopyright:

© 2006 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

[1] Weetall, H. H. App. Biochem. Biotech. 1993, 41, 157.

Google Scholar

[2] Gill, I. Chem. Mater. 2001, 13, 3404.

Google Scholar

[3] Carrado, K. A.; Macha, S. M.; Teide, D. M. Chem. Mater. 2004, 16, 2559.

Google Scholar

[4] Kumar, C. V.; Chaudhari, A. Chem. Mater. 2001, 13, 238.

Google Scholar

[5] Vinu, A.; Streb, C.; Murugesan, V.; Hartmann, M. J. Phys. Chem. B 2003, 107, 8297.

Google Scholar

[6] Han, Y. J.; Stucky, G. D.; Butler, A. J. Am. Chem. Soc. 1999, 121, 9897.

Google Scholar

[7] Takahashi, H.; Li, B.; Sasaki, T.; Miyazaki, C.; Kajino, T.; Inagaki, S. Chem. Mater. 2000, 12, 3301.

Google Scholar

[8] Washmon-Kriel, L.; Jimenez, V. L.; Balkus, K. J. J. Molec. Cata. B.: Enyzmatic 2000, 10, 453.

Google Scholar

[9] Yiu, H. H. P.; Wright, P. A.; Botting, N. P. J. Molec. Cata. B.: Enyzmatic 2001, 15, 81.

Google Scholar

[10] Yiu, H. H. P.; Botting, C. H.; Botting, N. P.; Wright, P. A. Phys. Chem. Chem. Phys. 2001, 3, 2983.

Google Scholar

[11] Deere, J.; Magner, E.; Wall, J. G.; Hodnett, B. K. J. Phys. Chem. B 2002, 106, 7340.

Google Scholar

[12] Deere, J.; Magner, E.; Wall, J. G.; Hodnett, B. K. Catalysis Letters 2003, 85, 19.

DOI: 10.1023/a:1022156405117

Google Scholar

[13] Vinu, A.; Murugesan, V.; Tangermann, O.; Hartmann, M. Chem Mater 2004, 16, 3056.

Google Scholar

[14] Blin, J. L.; Gerardin, C.; Carteret, C.; Rodehuser, C.; Selve, C.; Stebe, M. J. Chem. Mater. 2005, 17, 1479.

Google Scholar

[15] Lei, C.; Shinn, Y.; Liu, J.; Ackermann, E. J. J. Am. Chem. Soc. 2002, 124, 11242.

Google Scholar

[16] Smith, K.; Silvernail, N. J.; Rodgers, K. R.; Elgren, T. E.; Castro, M.; Parker, R. M. J. Am. Chem. Soc. 2002, 124, 4247.

Google Scholar

[17] Blanco, R. M.; Terreros, P.; Fernandez-Perez, M.; Otero, C.; Diaz-Gonzalez, G. J. Molec. Cata. B.: Enyzmatic 2004, 30, 83.

Google Scholar

[18] Kisler, J. M.; Stevens, G. W.; O'Connor, A. J. Mater. Phys. Mech. 2001, 4, 89.

Google Scholar

[19] Fan, J.; Lei, J.; Wang, L.; Yu, C.; Tu, B.; Zhao, D. Chem. Comm. 2003, 2140.

Google Scholar

[20] Moller, K.; Bein, T.; Fischer, R. X. Chem. Mater. 1998, 10, 1841.

Google Scholar

[21] Corma, A.; Kan, Q.; Navarro, M. T.; Perez-Pariente, J.; Rey, F. Chem. Mater. 1997, 9, 2123.

Google Scholar

[22] Zhao, D.; Huo, Q.; Feng, J.; Chmelka, B. F.; Stucky, G. D. J. Am. Chem. Soc. 1998, 120, 6024. (23) Mauk, A. G. Cytochrome c, A multidisciplinary approach; University Science Books: Sausalito, CA, (1996).

Google Scholar

[24] Oesterhelf, D.; Stoeckenius, W. Methods Enzymol. 1974, 31A, 667.

Google Scholar

[25] Firestone, M. A.; Wolf, A. C.; Seifert, S. Biomacromolecules 2003, 4, 1539.

Google Scholar

[26] Barrett, E. P.; Joyner, L. G.; Halenda, P. P. J. Am. Chem. Soc. 1951, 73, 373.

Google Scholar

[27] Broekhoff, J. C. P.; de Boer, J. H. J. Catal. 1968, 10, 377.

Google Scholar

[28] Babul, J.; Stellwagen, E. Biochemistry 1972, 11, 1195.

Google Scholar

[29] Rosell, F.; Mauk, A. G. Biochemistry 2002, 41, 7811.

Google Scholar

[30] Goto, Y.; Calciano, L. J.; Fink, A. Proc. Natl. Acad. Sci. USA 1990, 87, 573.

Google Scholar

[31] Peisach, J.; Blumberg, W. E.; Ogawa, S.; Rachmilewitz, E. A.; Oltzik, R. J. Biol. Chem. 1971, 246, 3342.

Google Scholar

[32] Telford, J. R.; Tezcan, F. A.; Gray, H. A.; Winkler, J. R. Biochemistry 1999, 38, 194.

Google Scholar