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Fabrication of SiO2-Coated Magnetic Nanoparticles for Applications to Protein Separation and Purification

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Abstract:

Coating of -Fe2O3 nanoparticles with SiO2 layer by wet chemical synthesis and its applications to protein separation and purification were investigated. The average particle size of -Fe2O3 core was 20 nm and SiO2 layer thickness was 5 nm. The band of OH- radicals on SiO2 layer was detected between 3600 and 3200 cm-1 in wave numbers, which showed that the surface property of coated nanoparticles was similar to that of conventional fumed silica. Finally, the feasibility of -Fe2O3/SiO2 nanoparticles for magnetic separation media in various bio processes was discussed in terms of structural and functional properties such as pore structure and magnetic properties.

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Info:

Periodical:

Materials Science Forum (Volumes 449-452)

Pages:

1033-1036

DOI:

https://doi.org/10.4028/www.scientific.net/MSF.449-452.1033

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Online since:

March 2004

Authors:

S.H. Yun, C.W. Lee, Jai Sung Lee, C.W. Seo, E.K. Lee

Keywords:

Coating of Nanoparticles, Separation and Purification, SiO2 Layer, γ-Fe2O3

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© 2004 Trans Tech Publications Ltd. All Rights Reserved

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