Papers by Author: Young Sun Kwon

Abstract: The purpose of this study is to evaluate the new bone formation of sinus augmentation with using ICB (Irradiated Cancellous Bone & Marrow; Rockey Mountain Tissue Bank, Denver, Co) and MBCP (Micro-Macroporous Biphasic Calcium Phosphate;Biomatlante, France). Study population consisted of 4 patients with maxillary posterior edentulous dentition and ridge heights were less than 5 mm. ICB (Rockey Mountain Tissue Bank, Denver, Co) and MBCP (Biomatlante, France) is mixed with 50: 50. After 6 months, the bone biopsies were done with 2mm trephine bur from lateral window opening. Mean new bone formations were 26.84 %, the residual grafts were 4.92 and soft tissues were 67.98 %. The small number of biopsies did not permit analysis of statistical significance. The variability of individual patient factors do not permit definitive conclusions. The mixtures of ICB & MBCP were superior or comparable to another various bone alternative materials in new bone formation of sinus floor elevation.

Abstract: This study evaluated the histology results of surgically created bone cavities in the calvaria of rabbits that were subsequently filled with a HA/ß-TCP composite powder developed in Korea (Dentium, Korea). Ten young adult rabbits were used. Four defects were surgically produced in the calvaria of each rabbit. These defects were classified into 4 groups: the control group, no graft materials; experimental group I, normal saline + graft materials; experimental group II, venous blood + graft materials; and experimental group III, graft materials only. The defects were randomly filled with the graft materials. The rabbits were sacrificed with at 1-, 2-, 4-, 6- and 8- weeks after surgery. The histology specimens were prepared using the general method with H & E staining at a 6 ㎛ thickness. Histologically, the degree of new bone formation was similar in all experimental groups. However, for experimental group II, many cells had gathered around the graft materials 1-week after surgery, and new bone formed slightly faster and than in the other groups. No bone formation was observed in the control group. Based on histology findings, the new HA/ß- TCP composite powders appeared to act as a scaffolding material for the regeneration of osseous defects.

Abstract: This study evaluated the efficacy of periodontal tissue regeneration using guided tissue regeneration (GTR) with a mixture of tooth ash and plaster as a bone substitute material in the treatment of class II furcation defects in dogs. GTR was performed at the site of a surgically formed mandibular premolar bifurcation area in dogs. Four adult dogs were used in the animal study. The animals were in a good periodontal state without any systemic disease. A resorbable membrane (Bio-Gide®, Swiss) and bone graft material using a mixture of tooth ash and plaster were used to examine the biological activity. The defect in the control group was filled a Bio-Gide® only. For the experimental group, the defects were filled with a mixture of tooth ash and plaster and covered by a Bio-Gide®. Oral rinsing with 0.12% chlorhexidine was performed twice a day for 2 weeks. In control group, new bone formation was observed adjacent to the preexisting bone. Soft tissue ingrowth was also noted. In experimental group, new lamellar type trabecular bone formation as well as centum and PDL regeneration was observed in the base of the infrabony pocket. More bone regeneration would be expected when GTR is performed using a mixture of human tooth-ash and plaster of Paris as a bone graft material.