Papers by Keyword: Angioplasty

Abstract: Objective This study aimed to investigate the Cytotoxic effects of TGFα-SAP on the inhibition of neointimal proliferation after rat common carotid arterial injury. Methods seventy rats were divided into two groups. The TGFα-SAP treated group was treated with local injection of TGFα-SAP (5μg/kg) after injury, and the control group was treated with saline. Rat arterial segment was investigated at 1, 3, 9, and 28 days after operation. Results Compared to the control group, the TGFα-SAP treated group shows a significant inhibition of intimal thickness. Conclusion The results indicated that TGFα-SAP can effectively inhibit neointimal proliferation following arterial injury .

Abstract: Thermoelastic Stress Analysis (TSA) is a non-contacting technique that provides full field stress information and can record high-resolution measurements from small structures. The work presented in this paper summarises the application of TSA to two types of small medical devices that are used to treat diseased arteries; angioplasty balloons and vascular stents. The use of high resolution optics is described along with a calibration methodology that allows quantitative stress measurements to be taken from the balloon structure. A brief account of a study undertaken to characterise the thermoelastic response from Nitinol is also included and it is demonstrated that thermoelastic data can be obtained from a stent at high resolutions.