Papers by Keyword: Bone Graft Material

Abstract: Calcium sulfate used in this study is newly fabricated to overcome its disadvantages; brittleness, difficult handling properties, rapid resorption and reaction heating. Especially when calcium sulfate is used in the graft procedure, it is difficult to control the setting time, solubility into blood and body fluid. To improve the handling properties, Calcium sulfate is mixed with Carboxylmethylcellulose (CMS). The putty type calcium sulfate used in the present study presented lower values in cementum formation and new bone formation than the control group. This may be due to use of poor osteoinductive calcium sulfate alone in the defect, limiting new bone formation. In addition, complete resorption of calcium sulfate after 8 weeks presents that addition of polymer failed to delay the resorption rate of calcium sulfate. Rather, it seemed to disturb the natural healing of the defect when compared with the findings in the control group. But the favorable result of calcium sulfate is shown when used with alloplast. The material used in the present study was developed for easier formability and manipulation avoiding scattering or dissolving of the material with blood or body fluid. However, the results reveal that further studies on effect of calcium sulfate with various other bone graft materials and ideal ratios in mixing the two should be determined in the future.However, the results reveal that further studies on effect of calcium sulfate with various other bone graft materials and ideal ratios in mixing the two should be determined in the future.

Abstract: This study evaluated periodontal repair and biomaterial reaction following implantation of a newly fabricated calcium phosphate chitosan block bone and chitosan membrane on the regeneration of 1- wall intrabony defects in the beagle dogs. The surgical control group received a flap operation only, while experimental group was treated with calcium phosphate chitosan block bone and/or chitosan membrane. All dogs were uneventful healing without any complication. The subjects were sacrificed 8 weeks after the experimental surgery, and a comparative histological and histometric examination was done. Chitosan membrane group significantly enhanced bone regeneration compared to control, CaP-chitosan block bone and combination group. Chitosan membrane remnants were observed in chitosan and combination group, while CaP-chitosan bone materials were resorbed completely. These results suggest that Chitosan membrnae significantly enhanced bone and cementum formation in advanced periodontal defects.

Abstract: The purpose of this study was to evaluate histologically the effect of LiF-maleic acid added calcium aluminate (LM-CA) bone cement and calcium aluminate-polymethylmethacrylate (CA-PMMA) composite bone cement on bone regeneration in rat calvarial defect. After calvarial defects in 8 mm in diameter were created, three groups of 10 animals, a total of 30, each either received LM-CA bone cement, CA-PMMA composite bone cement or a sham-surgery control. Histologic analysis was done at 2 weeks and 8 weeks of healing periods. We concluded that LM-CA bone cement can be used as a bioactive bone graft material due to ability of bonding to the existing bone and CA-PMMA can be used as a graft material for augmentation of bone-volume due to dimensional stability.

Abstract: This study evaluated the effects of mixture of fibrin-fibronectin sealant system(FFSS) and calcium carbonate(CC) in periodontal intrabony defects. Thirty six sites with two or three wall intrabony defect were used. 14 defects treated with periodontal flap surgery were assigned as the control group. 11 defects treated with CC implantation were designed as experimental group 1 and 11 defects, treated with CC and FFSS implantation as experimental group 2. The control and experimental groups all achieved statistically significant improvements in probing depth and clinical attachment level from the baseline (P<0.01). In mean postsurgery probing depth and gingival recession reduction, there were no statiscally significant differences between the experimental groups and the controls. However, mean postsurgery clinical attachment levels of both experimental groups improved significantly more than that of the controls. As a result, we suggest that mixture of FFSS and CC can be used effectively in intrabony defect as osteoconductive materials.