Papers by Keyword: Salt Leaching

Abstract: Tissue engineering process has developed renewable materials used in a variety of applications. This research selected gelatin blended with CMC and fabricated by using salt-leaching technique. This technique does not require solvent, pressure or unnecessary expensive devices. The ratios of gelatin/CMC were 100/0(G1), 90/10(G2), 80/20(G3), 70/30(G4) and 60/40(G5), respectively. Crosslinking technique by using high temperature or dehydrothermal treatment (DHT) for improvement the properties of gelatin sponges brought to use in this research. The scaffolds were characterized the physical properties by observing the morphology using Scanning Electron Microscope (SEM) and measuring pore size of the scaffold from SEM images. The SEM images results revealed that the scaffolds occurred inter-connected porous structures which were found in 80/20 (G3), 70/30 (G4), and 60/40 (G5). The pore size of all scaffolds was in range of 113.46-212.82 μm. The compressive results revealed that the G3 scaffold occurred the highest compressive modulus which was 184 kPa whereas the mixture of 60/40(G5) ratio had lowest compressive modulus which was 23 kPa and the mixture 90/10(G2), 100/0(G1) and 70/30(G4) ratio were 75, 70 and 46 kPa, respectively.

Abstract: This paper reports a preliminary study on the development and characterization of a porous calcium phosphate glass-ceramic for tissue engineering application. To obtain porous glass scaffolds, a mixture of 3CaO.P2O5-SiO2-MgO glass (grain size below 20 'm) and NaCl with 200- 300 'm of particle size was taken in the volume proportion 1:1. The mixture was shaped into cylindrical samples (10 mm diameter x 10 mm thick) by using unidirectional pressing. The sintering thermal cycle was selected by means of thermal analyses (DTA/TG and dilatometry) in order to attain a high enough cohesion among the glass particles. After thermal consolidation, the salt was dissolved in water, resulting in highly porous materials. The effect of the sintering thermal cycle on the structure and microstructure characteristics of the scaffolds was investigated in this paper.