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Fabrication of Encapsulated Silicagel Microsphere with Hydroxyapatite for Sustained-Release

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Abstract:

Apatite nuclei were precipitated in the pores of silicagel microspheres by raising pH of simulated body fluid (SBF). By a soak in SBF, hydroxyapatite (HAp) was induced from the apatite nuclei and spread over whole surface area of the silicagel microspheres. Then encapsulated silicagel microspheres with HAp were fabricated.

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Info:

Periodical:

Key Engineering Materials (Volumes 396-398)

Pages:

519-522

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.396-398.519

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Online since:

October 2008

Authors:

Shihori Yamane, Takeshi Yabutsuka, Mitsuhiro Hibino, Takeshi Yao

Keywords:

Apatite Nucleus (AN), Biomimetic Method, Hydroxyapatite (HAP), Microcapsule, Silica Gel, Simulated Body Fluid (SBF)

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© 2009 Trans Tech Publications Ltd. All Rights Reserved

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