Structural and Tissue Reaction Properties of Novel Hydroxyapatite Ceramics with Unidirectional Pores

Yasushi Suetsugu; Yuji Hotta; Masashi Iwasashi; Masataka Sakane; Masanori Kikuchi; Toshiyuki Ikoma; Tatsuhiko Higaki; Naoyuki Ochiai; M. Tanaka

doi:10.4028/www.scientific.net/KEM.330-332.1003

Paper Titles

Bone Ingrowth Into Porous Bioactive Titanium Implant for Load-Bearing Use: Experimental Study Using a Novel Canine Anterior Interbody Fusion Model
p.987

Biomimetic Apatite/Polycaprolactone (PCL) Nanofibres for Bone Tissue Engineering Scaffolds
p.991

Structure and Antibacterial Properties of Ag-Doped TiO₂ Porous Materials
p.995

Comparison of Porous Ti₆Al₄V Made by Sponge Replication and Directly 3D Fiber Deposition and Cancellous Bone
p.999

Structural and Tissue Reaction Properties of Novel Hydroxyapatite Ceramics with Unidirectional Pores
p.1003

Hydroxyapatite/Chondoroitin Sulfate Microparticles as Time-Controlled Release Carrier of Proteins
p.1009

Adsorption and Effectiveness of Different Antibiotics on Pure Hydroxyapatite (HA) with Controlled Porosity
p.1013

Setting Behaviors and Ciprofloxacin Hydrochloride Sustained Release of CSH-TCP Binary Cement
p.1017

Novel Gene-Transferring System Using a Laminin-DNA-Apatite Composite Layer
p.1021

HomeKey Engineering MaterialsKey Engineering Materials Vols. 330-332Structural and Tissue Reaction Properties of Novel...

Structural and Tissue Reaction Properties of Novel Hydroxyapatite Ceramics with Unidirectional Pores

Abstract:

Porous ceramics of hydroxyapatite was fabricated utilizing the crystal growth of thin ice columns parallel to one another in gelatin gel containing hydroxyapatite nanoparticles. The obtained ceramics possessed unidirectional pore channels with a porosity of around 75% and showed compressive strength of up to 13.1 MPa. As control materials, porous hydroxyapatite ceramics with a directionless pore structure were also fabricated by isotropic freezing and compared with the unidirectional samples regarding compressive strength and tissue reaction in vivo. Although the porosity and pore size distribution were similar, the compressive strength and new bone formation ability of the unidirectional samples were significantly greater than those of the random structured porous ceramics.