Paper Titles
Preparation of Nano-Sized Strontium Containing Tricalcium Phosphate Particles
p.263
Remineralization Effect of the Nano-HA Toothpaste on Artificial Caries
p.267
Effect of Precipitation Method on Stoichiometry and Morphology of Hydroxyapatite Nanoparticles
p.271
Remineralization Potential of Sports Drink Containing Nano-Sized Hydroxyapatite
p.275
Influence of Different Hydroxyapatite Particles on the Behavior of Highly Malignant Melanoma Cells
p.279
Research about Tooth Whitening and Bacteria Sticking Capability with Using Dentifrice Including Nano-Hydroxyapatite, Sodium Metaphosphate
p.283
Effect of Nanometer Hydroxyapatite Particles on Rat Macrophage at mRNA Level
p.287
Effect of New Dentifrice Containing Nano-Sized Carbonated Apatite on Enamel Remineralization
p.291
Synthesis and Characterization of Yttrium/Hydroxyapatite Nanoparticles
p.295

Influence of Different Hydroxyapatite Particles on the Behavior of Highly Malignant Melanoma Cells

Article Preview

Abstract:

The aim of this study is to reveal the response of highly malignant tumor cell to different hydroxyapatite particles. Human’s highly malignant melanoma (MM) cell line A875 is exposed to two kinds of short-rod hydroxyapatite particles. After incubated with hydroxyapatite particles at different time points, the effects of MM cell morphology, proliferation and invasion are evaluated by SEM, MTT, and MMP2 protein immunohistochemistry respectively. SEM figures show that superficial sentus of MM cells reduce; more secretion is found; and smaller HA particles have more obvious effect. At the same time, no statistic difference can be found in MTT assay and MMP2 expression measurement. This study also provides useful information about biosecurity of hydroxyapatite ceramic in transplantation after highly malignant tumor excision.

You might also be interested in these eBooks
Bioceramics 19 View Preview

Info:

Periodical:

Key Engineering Materials (Volumes 330-332)

Pages:

279-282

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.330-332.279

Citation:

Cite this paper

Online since:

February 2007

Authors:

B. Guo, B. Li, Xin Long Wang, M.X. Zhang, N.H. Yan, Xing Dong Zhang

Keywords:

Hydroxyapatite Particle, Malignant Melanoma Cell, Matrix Metalloproteinase

Export:

RIS, BibTeX

Price:

Permissions CCC:

Request Permissions

Permissions PLS:

Request Permissions

Сopyright:

© 2007 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

References

[1] Bloebaum RD, Zou L, Bachus KN, et al: Clin Orthop vol. 338 (1997), P. 109.

Google Scholar

[2] Bloebaum RD, Beeks D, Dorr LD, et al: Clin Orthop vol. 298 (1994), P. 19.

Google Scholar

[3] Patrice Laquerrierea, , Alexia Grandjean-Laquerriereb, Salima Addadi-Rebbah, et al: Biomaterials vol. 25 (2004),P. 2515.

Google Scholar

[4] Alexia Grandjean-Laquerrierea, Patrice Laquerriereb, 1, Dominique Laurent-Maquinc, et al: Biomaterials vol. 25 (2004),P. 5921.

Google Scholar

[5] Robert N, Fabricant, Joseph E, et al: Proc Natl Acad Sci vol. 74 (1977), P. 565.

Google Scholar

[6] Alexia Grandjean-Laquerrierea, Patrice Laquerriereb, Moncef Guenounouc, et al: Biomaterials vol. 25 (2005), P. 2361.

Google Scholar

[7] MacDougall JR, Matrisian LM: Cancer Metastasis RV vol. 14(1995), P. 351.

Google Scholar