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Biomimetic Organic-Inorganic Nanocomposite Coatings for Titanium Implants. II. Biological "In Vitro" and "In Vivo" Characterization

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Abstract:

Biological mineralization proceeds within an organic matrix and is induced and controlled by extracellular, highly acidic matrix macromolecules. Our group has recently prepared organic-inorganic nanocomposite coatings by a strategy that closely mimics these processes. The strategy involves depositing a matrix of polyelectrolyte multilayers (PE MLs), alternating with layers of amorphous calcium phosphate (ACP) particles, then "in situ" growing nanosized apatite crystals within that matrix [1, 2]. Here we describe the results of biological "in vitro" and "in vivo" testing of these materials.

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Periodical:

Key Engineering Materials (Volumes 330-332)

Pages:

401-404

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.330-332.401

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Online since:

February 2007

Authors:

M. Dutour Sikirić, Rene Elkaim, S. Lamolle, H.J. Ronold, S.P. Lyngstadass, Helga Füredi-Milhofer, F. Cuisinier

Keywords:

Bioimplants, Biological Test, Composite Coating, Octacalcium Phosphate, Polyelectrolyte Multilayer

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© 2007 Trans Tech Publications Ltd. All Rights Reserved

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