Paper Titles
Thermophysical and Mechanical Properties of β-Tricalcium Phosphate Reinforced Polyhydroxybutyrate and Polyhydroxybutyrate-Co-Hydroxyvalerate Composites
p.1217
Fabrication and Characterization of Composite Microspheres Containing Carbonated Hydroxyapatite Nanoparticles
p.1221
Selective Laser Sintering of Tissue Engineering Scaffolds Using Poly(L-Lactide) Microspheres
p.1225
Fabrication and Characterisation of Polymer and Composite Scaffolds Based on Polyhydroxybutyrate and Polyhydroxybutyrate-Co-Hydroxyvalerate
p.1229
Effects of Processing Parameters on the Morphology and Size of Electrospun PHBV Micro- and Nano-Fibers
p.1233
Hydroxyapatite Nano-Particles Coating on the Pore Surface Within Poly(DL-lactic-co-glycolic acid) Scaffold
p.1237
Modelling of Extrusion Behaviour of Biopolymer and Composites in Fused Deposition Modelling
p.1241
Effect of Artificial Cartilage Made up of Smart Material of Nanostructure on Dispersion in Poorly Conducting Macromolecular Components in Synovial Joints
p.1245
Bioactive Composite Coating on Titanium Implants for Hard Tissue Repair
p.1249

Effects of Processing Parameters on the Morphology and Size of Electrospun PHBV Micro- and Nano-Fibers

Article Preview

Abstract:

Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) was used to fabricate micro- and nano-fibrous, non-woven mats by electrospinning for potential tissue engineering applications. The morphology and size of electrospun fibers were assessed systematically by varying the processing parameters. It was found that the diameter of the fibers produced generally increased with electrospinning voltage, needle diameter for the polymer jet and polymer solution concentration. Beaded fibers were readily produced at low PHBV concentrations, whereas the needle was blocked within a very short time during electrospinning when the PHBV concentration was too high. At the polymer concentration of 7.5 % w/v, it was shown that beadless PHBV fibers could be generated continuously by adjusting the electrospinning parameters to appropriate values. This study has clearly demonstrated that electrospinning can be an effective technique to produce PHBV micro- and nano-fibers. It has also been shown that composite fibers containing hydroxyapatite (HA) can be produced using the electrospinning technique.

You might also be interested in these eBooks
Advances in Composite Materials and Structures View Preview

Info:

Periodical:

Key Engineering Materials (Volumes 334-335)

Pages:

1233-1236

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.334-335.1233

Citation:

Cite this paper

Online since:

March 2007

Authors:

Ho Wang Tong, Min Wang

Keywords:

Electro-Spinning, Microfiber, Nanofiber, PHBV, Scaffold, Tissue Engineering

Export:

RIS, BibTeX

Price:

Permissions CCC:

Request Permissions

Permissions PLS:

Request Permissions

Сopyright:

© 2007 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

References

[1] Y. Ito, H. Hasuda, M. Kamitakahara, C. Ohtsuki, M. Tanihara, I.K. Kang, O.H. Kwon, Journal of Bioscience and Bioengineering, 100 (2005), 43 - 49.

DOI: 10.1263/jbb.100.43

Google Scholar

[2] J.S. Choi, S.W. Lee, L. Jeong, S.H. Bae, B.C. Min, J.H. Youk, W.H. Park, Journal of Biological Macromolecules, 34 (2004), 249 - 256.

Google Scholar

[3] C.T. Laurencin, A.M.A. Ambrosio, M.D. Borden, J.J. Cooper, Annual Review of Biomedical Engineering, Vol. 1, 19 - 46, (1999).

Google Scholar

[4] C.Y. Xu, R. Inai, M. Kotaki, S. Ramakrishna, Biomaterials, 25 (2004), 877 - 886.

Google Scholar

[5] W.Y. Zhou, M. Wang, W.L. Cheung, Proceedings of the International Symposium on Quality of Bone and Scaffold Materials Evaluated by microCT, pQCT and MRI, Hong Kong, 2005, 166.

Google Scholar

[6] G.L. Bowlin, K.J. Pawlowski, E.D. Boland, D.G. Simpson, J.B. Fenn, G.E. Wnek, J.D. Stitzel, in Tissue Engineering and Biodegradable Equivalents: Scientific and Clinical Applications, Edited by K.U. Lewandrowski, New York, USA: Marcel Dekker, 2002, 165 - 178.

Google Scholar

[7] G.E. Wnek, M.E. Carr, D.G. Simpson, G.L. Bowlin, Nano Letters, 3 (2003), 213 - 216.

Google Scholar

[8] Z. Ma, M. Kotaki, R. Inai, S. Ramakrishna, Tissue Engineering, 11 (2005), 101 - 108.

Google Scholar