Crosslinked Gelatin Nanofibers and their Potential for Tissue Engineering

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Abstract:

Gelatin nanofibers were obtained by the use of TFE/deionized water co-solvent system without adding any other fiber forming material. The diameter of nanofibers was in the rage from 200 to 360 nm. The water-resistant ability and mechanical properties of electrospun gelatin nanofibers were improved by crosslinking in GTA or FA vapor, which increased with crosslinking time. Cytotoxicity evaluation indicates that the crosslinked gelatin membranes support the proliferation of human dermal fibroblast.

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Key Engineering Materials (Volumes 342-343)

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169-172

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July 2007

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© 2007 Trans Tech Publications Ltd. All Rights Reserved

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[1] M.E. Nimni, D.T. Cheung, B. Strates, M. Kodama and K. Sheikh, in: Bioprosthesis Drived from Cross-linked and Chemically Modified Collagenous Tissues, edited by M.E. Nimni, vol. 3 of Collagen, CRC Press, Boca Raton (1988).

Google Scholar

[2] T. Nishido, K. Yasumoto, T. Otori and J. Desaki: Invest. Ophthalmol. Vis. Sci. Vol. 29 (1988), p.1887.

Google Scholar

[3] C. S Ki, D. H Baek, K.D. Gang, K.H. Lee, I.C. Um and Y.H. Park: Polymer Vol. 46 (2005), p.5094.

Google Scholar

[4] M.T. Sheu, J.C. Huang, G.C. Yeh and H.O. Ho: Biomaterials, Vol. 22 (2001), p.1713.

Google Scholar

[5] T. Mosmann: J. Immunol. Methods, Vol. 65 (1983), p.55.

Google Scholar

[6] Z.M. Huang, Y.Z. Zhang, S. Ramakrishna and C.T. Lim: Polymer Vol. 45 (2004), p.5361.

Google Scholar

[7] K.H. Lee, H.Y. Kim, Y.J. Ryu, K.W. Kim and S.W. Choi: J. Polym. Sci. Part B: Polym. Phys., Vol. 41 (2003), 1256.

Google Scholar

[8] A. Jayakrishnan and S.R. Jameela: Biomaterials, Vol. 17 (1996), p.471 Culture Time (h) 2 24 72 Absorbance 0. 0 0. 2 0. 4 0. 6 0. 8 1. 0 1. 2 1. 4 1. 6 FA 1h FA 3h FA 5h GTA 1h GTA 3h GTA 5h.

Google Scholar