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Preparation of Naphthalocyanine Dendrimer Loaded Polyion Complex Micelle for Photodynamic Therapy

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Abstract:

A naphthalocyanine dendrimer (DNPcZn) was synthesized as a potential candidate of photosensitizer for photodynamic therapy. DNPcZn exhibited strong Q band absorption around 780 nm, a useful wavelength for high tissue penetration. A polyion complex (PIC) micelle (DNPcZn/m) system was formed via an electrostatic interaction of anionic DNPcZn and poly(ethylene glycol)-poly(L-lysine) block copolymers (PEG-b-PLL).

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Advanced Biomaterials VII View Preview

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Periodical:

Key Engineering Materials (Volumes 342-343)

Pages:

465-468

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.342-343.465

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Online since:

July 2007

Authors:

Woo Dong Jang, Nobuhiro Nishiyama, Kazunori Kataoka

Keywords:

Dendrimer, Micelle, Naphthalocyanine, Photodynamic Therapy, Photosensitizer

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© 2007 Trans Tech Publications Ltd. All Rights Reserved

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