In Vivo and In Vitro Tendon Engineering

Feng Xu; Wei Liu; Xian Wei; Hong Li; De Jun Cao; Yi Lin Cao

doi:10.4028/www.scientific.net/KEM.342-343.9

Paper Titles

Organizers

Preface

Reconstruction of Kidney-Like Tissue Using ECM Gel and Rat Embryonic Kidney Fragments
p.1

The Bone Remodeling and Cellular Responses to Cranial Suture Distraction Osteogenesis in Growing Goats
p.5

In Vivo and In Vitro Tendon Engineering
p.9

Microscopic Multi-Directional Mechanical Properties of Human Femoral Cancellous Bone Tissue
p.13

Fibrinogen Concentration Influence on VEGF-Induced Differentiation of Adipose Tissue-Derived Stem Cells into Endothelial Cells
p.17

Fibroblasts-Populated Fibrin Membrane Enhance Wound Closure
p.21

Development of Efficient Cardiac Differentiation Method of Mouse Embryonic Stem Cells
p.25

HomeKey Engineering MaterialsKey Engineering Materials Vols. 342-343In Vivo and In Vitro Tendon Engineering

In Vivo and In Vitro Tendon Engineering

Abstract:

Tendon is an important supportive tissue of human body responsible for normal physical activity. However, tendon damage and defect remain an important factor for causing disability. The rise of tissue engineering technology provides an effective means of tendon reconstruction and repair, which will bring promise for functional recovery. In our center, tendon engineering is one of major research areas. We have performed the in vivo study by using tenocytes and polyglycolic acid fibers to reconstruct and repair tendon defect in hen and porcine models. The results demonstrated the successful regeneration and repair of tendon defects created in different models. In addition, tendon function was also well recovered by generated autologous tendon tissue that possesses strong biomechanical property. Recently, we have also successfully generated tendon tissue in vitro by using static strain device and bioreactors, which could be potentially transplanted as the tendon graft for tendon defect repair.