Paper Titles
Evaluation of Biocompatibility of Porous Hydroxyapatite Developed from Edible Cuttlefish Bone
p.155
Production and Characterization of Zinc Substituted Hydroxyapatite
p.159
An Introduction of New Artificial Bone Unit “Tetra-Bone”
p.163
Surface Characteristics of HA and β-TCP Immersed in SBF
p.167
Development of Multisubstituted Apatites for Bone Reconstruction
p.171
The Role of Si Substitution into Hydroxyapatite Coatings
p.175
The Effect of Particle Morphologies on Mechanical Properties of Porous Hydroxyapatite Scaffold
p.179
In Vitro Synthesis of Calcium Nanoparticles Using the Protein Cage of Apoferritin
p.183
Characterization and Protein Adsorption Ability of Zinc, Iron and Magnesium Hydroxyapatite
p.187

Development of Multisubstituted Apatites for Bone Reconstruction

Article Preview

Abstract:

Hydroxyapatite powders characterized by substitutions of Mg2+, SiO4 4-, CO3 2- ions in biological like amounts, in the crystallographic site of calcium and phosphates, ions in biological like amounts, in the crystallographic site of calcium and phosphorus, were successfully prepared by synthesis in aqueous medium. The chemico-physical properties of the powders were investigated through several analytical techniques, among them: XRD, FTIR, TG-DTA, ICP-OES, HR-TEM. The entering of silicon in the HA structure progressively reduces its crystallinity, as also carbonate ions do. Silicate and carbonate ions can enter simultaneously into the HA structure, in biological-like amounts, although they compete for the occupation of the phosphate site. Solubility tests, carried out at physiological conditions, reveal an increased calcium release in the HA powders containing silicon compared to the silicon-free HA.

You might also be interested in these eBooks
Bioceramics 20 View Preview

Info:

Periodical:

Key Engineering Materials (Volumes 361-363)

Pages:

171-174

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.361-363.171

Citation:

Cite this paper

Online since:

November 2007

Authors:

Elena Landi, Simone Sprio, Monica Sandri, Anna Tampieri, Luca Bertinetti, Gianmario Martra

Keywords:

Carbonate, Magnesium, Non Stoichiometric Hydroxyapatite, Silicon, Solubility

Export:

RIS, BibTeX

Price:

Permissions CCC:

Request Permissions

Permissions PLS:

Request Permissions

Сopyright:

© 2008 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

References

[1] R.Z. Le Geros in: Calcium Phosphates in oral biology and medicine, edited by H. Myers, volume 15 of Monographs in Oral Science, Chapter 5, Karger AG Publishers (1991).

Google Scholar

[2] E. Landi, G. Celotti, A. Tampieri and G. Logroscino: J. Eur. Cer. Soc 23 (2003) p.2931.

Google Scholar

[3] E. Landi, A. Tampieri, G. Celotti, M. Mattioli Belmonte and G. Logroscino: Key Eng Mat 284- 286 (2005) p.949.

DOI: 10.4028/www.scientific.net/kem.284-286.949

Google Scholar

[4] N. Patel, I.R. Gibson, K.A. King, S. M. Best, P.A. Revell and W. Bonfield: J. Mater. Sci., Mater. Med 13 (2002) 1199.

Google Scholar

[5] L. Bertinetti, A. Tampieri, E. Landi, C. Ducati, P.A. Midgley, S. Cosuccia and G. Martra: J. Phys. Chem. C, 111 (2007) 4027-4035.

DOI: 10.1021/jp066040s

Google Scholar

[6] S. Sprio, A. Tampieri, E. Landi, M. Sandri, S. Martorana, G. Celotti and G. Logroscino: Mater Sci Eng. (2006).

Google Scholar