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Glass-Ceramic Scaffolds and Shock Waves Effect on Cells Migration

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Abstract:

Glass-ceramic scaffolds for bone grafting have been prepared using the sponge replication method and a highly bioactive silica based glass belonging to the system SiO2-P2O5- CaO-MgO-Na2O-K2O (CEL2). The parameters for the sponge impregnation were optimized in order to obtain a continuous coating of the polymeric skeleton which will lead, after the polymeric phase removal, to a resistant macroporous glass-ceramic template. A complete characterization was carried out on the obtained scaffold in order to assess its morphology and specifically its porosity and the degree of pores interconnection. A human osteoblasts cells line (MG-63) was cultured onto the scaffold and the effect of stimulation with shock waves on the cell ability of colonizing the scaffold was investigated.

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Periodical:

Key Engineering Materials (Volumes 361-363)

Pages:

233-236

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.361-363.233

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Online since:

November 2007

Authors:

Chiara Vitale-Brovarone, Francesco Baino, Germana Martinasso, Rosangela Canuto, Francesco Bassi, Enrica Verné

Keywords:

Bone Grafting, Glass-Ceramic Scaffold, Osteoblasts Migration, Shock Waves

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© 2008 Trans Tech Publications Ltd. All Rights Reserved

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