Foamed β-Tricalcium Phosphate Scaffolds

Edgar Benjamin Montufar; C. Gil; Tania Traykova; Maria-Pau Ginebra; Josep A. Planell

doi:10.4028/www.scientific.net/KEM.361-363.323

Paper Titles

Effect of Mechanical Mixing and Powder to Liquid Ratio on the Strength and Reliability of a Brushite Bone Cement
p.307

Modifying Brushite Cement Degradation Using Calcium Alginate Beads
p.311

Strength and Chemical Stability Due to Aging of Two Bone Void Filler Materials
p.315

Apatite Foam Fabrication Based on Hydrothermal Reaction of α-Tricalcium Phosphate Foam
p.319

Foamed β-Tricalcium Phosphate Scaffolds
p.323

A Comparison of the Efficacy of Hydoxyapatite Based Cements and Gels as Drug Delivery Matrices
p.327

Development of Alkali Containing Calcium Phosphate Cements
p.331

Biological Evaluation of Chelate-Setting Apatite Cement Using Inositol Phosphate
p.335

Effect of Added Tricalcium Phosphate on Basic Properties of Apatite Cement
p.339

HomeKey Engineering MaterialsKey Engineering Materials Vols. 361-363Foamed β-Tricalcium Phosphate Scaffolds

Foamed β-Tricalcium Phosphate Scaffolds

Abstract:

The design and processing of 3D macroporous bioactive scaffolds is one of the milestones for the progress of bone tissue engineering and bone regeneration. Calcium phosphate based ceramics are among the most suitable materials, due to their similarity to the bone mineral. Specifically, beta-tricalcium phosphate (β-TCP) is known to be a resorbable and bioactive material, with well established applications as bone regeneration material. The aim of this work is to explore a new route to obtain β-TCP macroporous scaffolds starting from calcium phosphate cements. To this end foamed calcium phosphate cement, composed of alpha tricalcium phosphate as starting powder was used as initial material. The set foamed structures, made of calcium deficient hydroxyapatite (CDHA) were sintered to obtain the final β-TCP macroporous architecture. The interconnected macroporosity was maintained, whereas the porosity in the nanometric range was strongly reduced by the sintering process. The sintering produced also an increase in the mechanical properties of the scaffold.