Paper Titles
Microtensile Bond Strength of Dual-Cured Resin Luting Cements to Dentin by the Type of Dentin Adhesives
p.889
Biomineralization Studies in Age Induced Human Teeth
p.893
Preparation of Leucite Powder with Controlled c-Phase Fraction for a Variety of Dental Applications
p.897
Development of Modelling Methods for Materials to be Used as Bone Substitutes
p.903
Calcium Phosphate Coated Rapid Prototyped Porous Titanium Scaffolds
p.907
Newly Unsintered Bone Graft Substitutes with Controlled Porosity
p.911
Fabrication of Tailored Hydroxyapatite Scaffolds: Comparison between a Direct and an Indirect Rapid Prototyping Technique
p.915
Evaluation of Bone Ingrowth in Free Form Fabricated Scaffolds
p.919
Processing and Characterization of Apatite-Wollastonite Porous Scaffolds for Bone Tissue Engineering
p.923

Calcium Phosphate Coated Rapid Prototyped Porous Titanium Scaffolds

Article Preview

Abstract:

Porous Titanium Scaffolds were produced by using a rapid prototyping technique. These scaffolds were either coated or not with a calcium phosphate coating via an eletrodeposition method. Rat bone marrow mesenchymal stem cells were cultured on the scaffolds at a density of 106 cells/scaffold for a period of 3 days. Cell proliferation was measured by using the Alamar Blue assay. The scaffolds were observed by SEM and polarized light microscopy. Constructs were then implanted subcutaneously for 4 weeks in syngenic rats. Cells proliferated well after seeding. After subcutaneous implantation, histology and SEM revealed the presence of uniform coatings as well as Ca and P deposits in the non-coated scaffolds suggesting mineralization.

You might also be interested in these eBooks
Bioceramics 20 View Preview

Info:

Periodical:

Key Engineering Materials (Volumes 361-363)

Pages:

907-910

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.361-363.907

Citation:

Cite this paper

Online since:

November 2007

Authors:

Marco A. Lopez-Heredia, Borhane H. Fellah, Paul Pilet, C. Leroux, M. Dorget, Pierre Weiss, J. Sohier, Pierre Layrolle

Keywords:

Bone Marrow Cell, Coating, Electro-Deposition, Rapide Prototyping, Scaffold, Titanium (Ti)

Export:

RIS, BibTeX

Price:

Permissions CCC:

Request Permissions

Permissions PLS:

Request Permissions

Сopyright:

© 2008 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

References

[1] J. B. Park and R.S. Lakes. (1992) Biomaterials: An Introduction, 2nd Edition, Plenum Pub Corp.

Google Scholar

[2] D.C. Dunand (2004) Adv Eng Mater 6(6): 369-376.

Google Scholar

[3] G. Ryan, A. Pandit, D. Panagiotis et al (2006) Biomaterials 27(13): 2651-2670.

Google Scholar

[4] J.P. St. Pierre, M. Gauthier, L.P. Lefebvre, et al (2005) Biomaterials 26(35): 7319-7328.

Google Scholar

[5] E. Goyenvalle, E. Aguado, J-M. Nguyen et al (2006) Biomaterials 27(7): 1119-1128.

Google Scholar

[6] L. Le Guéhennec, A. Soueidan, P. Layrolle et al (2007) Dent Mater 23(7): 844-854.

Google Scholar

[7] M.A. Lopez-Heredia, P. Weiss and P. Layrolle (2007) J Mater Sci Mater Med 18(2): 381-390.

Google Scholar

[8] D. Fang, B-M Seo, Y. Liu et al (2007) Stem Cells 25(4): 1021-1028.

Google Scholar

[9] M.A. Lopez-Heredia, E. Goyenvalle, E. Aguado et al (2006) Key Eng Mater 309-311: 1099- 1102.

Google Scholar

[10] C.C. Silva and A.S.B. Sombra (2004) J Phys Chem Sol 65(5): 1031-1033.

Google Scholar