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Surface Modification of Hydrogels and Cell Adhesion

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Abstract:

Polymer hydrogels have many different functions in the field of tissue engineering and medicine. Modification of 2-hydroxy-ethyl-methacrylate (HEMA) and 2-ethyl-oxy-ethylmethacrylate (EOEMA) by plasma treatment performed in Ar atmosphere at RT for 0-400 s was studied using different techniques. Sample ablation was determined by gravimetry, surface wettability and aging by goniometry, chemical structure by FTIR spectroscopy and surface morphology by AFM microscopy. The plasma modification changes the sample surface morphology. In vitro cultivation shows that the plasma treatment changes the proliferation of human LEP cells.

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Periodical:

Materials Science Forum (Volumes 567-568)

Pages:

265-268

DOI:

https://doi.org/10.4028/www.scientific.net/MSF.567-568.265

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Online since:

December 2007

Authors:

Kateřina Kolářová, Nikola Kasálková, Barbora Dvořánková, Jiří Michálek, Václav Švorčík

Keywords:

Cells, Hydrogel, Methacrylate, Plasma

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© 2008 Trans Tech Publications Ltd. All Rights Reserved

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