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Biocompatibility of Phema and P(Hema-Co-Sma) Hydrogels

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Abstract:

To replace a poly(2-hydroxyethyl methacrylate) (PHEMA) sponge, which has limited applications as an implant material, PHEMA and poly(2-hydroxyethyl methacrylate-co-sodium methacrylate) (P(HEMA-co-SMA)) hydrogels with enhanced biocompatibility were prepared based on the copolymerization of 2-hydroxyethyl methacrylate (HEMA) and sodium methacrylate (SMA) at a high monomer concentration. When the cytotoxicity, cell adhesion, and in vivo tissue reaction of the resulting hydrogels were investigated, the results suggest that hydrogels prepared by the copolymerization of HEMA and SMA at a high monomer concentration have great potential as implant materials with an excellent biocompatibility.

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Info:

Periodical:

Key Engineering Materials (Volumes 277-279)

Pages:

51-55

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.277-279.51

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Online since:

January 2005

Authors:

Bo Hyung Park, Young A Han, Jin Hyun Choi, Jeong Ok Lim

Keywords:

Biocompatibility, Biomaterial, Cell Adhesion, Cytotoxicity, Implantation, In Vivo Tissue Reaction, Mechanically Strong Hydrogel, P(HEMA-Co-SMA), pHEMA

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© 2005 Trans Tech Publications Ltd. All Rights Reserved

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