Paper Titles
Surface Characterization and Antibacterial Evaluation of Poly(Ethylene Terephthalate) Modified by Chitosan-Immobilization
p.331
Nitrogen Plasma Source Ion Implantation (PSII) for Improvement of Blood-Compatibility of Silicon
p.335
Hemocompatibility of PET (Polyethylene Terephthalate) Films Grafted PEG (Polyethylene Glycol) by Plasma Surface Modification
p.339
Glucosamine Coating for Inhibiting Bacterial Adhesion to Titanium Surfaces
p.343
Physico-Chemical Modifications and Biological Improvements of Biomedical PET as a Consequence of Excimer LASER Irradiation
p.347
Effect of Rare Earth Y2O3 Content on Microstructure of Gradient Bioceramic Composite Coating Produced by Wide-Band Laser Cladding
p.351
The Mechanical Behavior of Water Vapor-Treated HA Coating Produced by Plasma Spraying Technique
p.355
Comparison in In Vitro Evaluation of Wollastonite and Dicalcium Silicate Coatings
p.359
The Effect of Bovine Serum Albumin on the Crystalline Characteristics of the CaP Biomimetic Coating
p.363

Physico-Chemical Modifications and Biological Improvements of Biomedical PET as a Consequence of Excimer LASER Irradiation

Article Preview

Abstract:

LASER Excimer irradiation can modify surface properties for biocompatibility improvement of a medical device. The PETs from 3 different origins were used in this study. The samples have been irradiated by excimer LASER with 10 different energies. The surface profile, the surface energy and the materials crystallinity have been assessed. Biological characterizations were made with human embryonic epithelial cells L132: proliferation, vitality, viability, adhesion with the p-NPP, and morphology. - The profile measurements allowed to establish the ablation threshold, which was 36 mJ/cm². The surface hydrophilic state increased reciprocally with the irradiation intensity. The gain is 13 %. The irradiated and non-irradiated product has identical cristallinity. PET was shown not to be toxic for L132 cells. Cell proliferation and cell vitality showed dose-dependant increases reciprocal to the irradiation energy (from 88 to 138% with respect to control). The correlation was highly significant (R² = 0,8). SEM micrographs show that the cells are better spread on the surface of irradiated PET than on untreated PET.

You might also be interested in these eBooks
Advanced Biomaterials VI View Preview

Info:

Periodical:

Key Engineering Materials (Volumes 288-289)

Pages:

347-350

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.288-289.347

Citation:

Cite this paper

Online since:

June 2005

Authors:

G. Mayer, N. Blanchemain, C. Dupas-Bruzek, M. Traisnel, D. Derozier, L.D. Laude, H.F. Hildebrand

Keywords:

Adhesion, Cell Viability, Cristallinity, Laser Excimer Irradiation, Polyethylene Teraphtalate (PET), Proliferation, Scanning Electron Microscope (SEM), Surface Energy, Surface Profile, Vitality

Export:

RIS, BibTeX

Price:

Permissions CCC:

Request Permissions

Permissions PLS:

Request Permissions

Сopyright:

© 2005 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

References

[1] J.C. Parodi, J.C. Palmaz and H.D. Barone: Ann Vasc Surg 1991, 5: 491-499.

Google Scholar

[2] J. Buth and R.J.F. Laheij: J Vasc Surg 2000, 31: 134-146.

Google Scholar

[3] L. De Bartolo, S. Morelli, A. Bader and E. Drioli: Biomaterials 2002, 23: 2485-2497.

Google Scholar

[4] H. Watanabe, T. Takata and M. Tsuge: Polym Int 1993, 31: 247-254.

Google Scholar

[5] L.D. Laude, D. Martinez, C. Dicara, F. Hanus and K. Kolev: Nucl Instr and Meth in Phys Res B 2001, 185: 147-155.

Google Scholar

[6] M. Lampin, R. Warocquier-Clerout, C. Legris, M. Degrange and M.F. Sigot-Luizard: J. Biomed Mater Res 1997, 36: 99-108.

DOI: 10.1002/(sici)1097-4636(199707)36:1<99::aid-jbm12>3.0.co;2-e

Google Scholar

[7] J.C. Hornez, A. Lefèvre, D. Joly and H.F. Hildebrand: Biomol. Engineering 2002, 19, 103-118.

Google Scholar

[8] S.A. Redey, M. Nardin, D. Bernache-Assolant, C. Rey, P. Delannoy, L. Sedel and P.J. Marie: J Biomed Mater Res 2000, 50: 353-364.

DOI: 10.1002/(sici)1097-4636(20000605)50:3<353::aid-jbm9>3.0.co;2-c

Google Scholar

[9] P. Linez-Bataillon, F. Monchau, M. Bigerelle and H.F. Hildebrand: Biomol Engineering 2002, 19, 133-142.

DOI: 10.1016/s1389-0344(02)00024-2

Google Scholar