Papers by Author: S. Singare

Abstract: In this paper, the authors describe a rapid prototyping method to produce vascularized tissue such as liver scaffold for tissue engineering applications. A scaffold with an interconnected channel was designed using a CAD environment. The data were transferred to a Polyjet 3D Printing machine (Eden 250, Object, Israel) to generate the models. Based on the 3D Printing model, a PDMS (polydimethyl-silicone) mould was created which can be used to cast the biodegradable material. The advantages and limitations of Rapid Prototyping (RP) techniques as well as the future direction of RP development in tissue engineering scaffold fabrication were reviewed.

Abstract: This paper reviews the applications of advanced technology such as CT, reverse engineering (RE), computer aided design (CAD) and rapid prototyping (RP) in medicine. We described: 1) the use of RP and medical imaging in surgical planning; 2) the design process for the production of customized medical implants by rapid prototyping; and 3) the fabrication of three-dimensional scaffolds for tissue engineering of human liver. In order to examine the applicability and efficiency of the rapid prototyping technology, some case studies are presented, involving visualization and surgical planning; the design of custom implant for cranial reconstruction; and the use of RP in the production of tissue scaffold. From the results, it has been shown that RP can be applied with high level of accuracy in surgical planning, custom implant and tissue engineering.