Papers by Keyword: Calcium Phosphate Blasting

Abstract: It was demonstrated that microstructured surfaces improve cell spreading and bone ingrowth. Particularly, the surface roughness modulates the osseointegration of orthopaedic and dental implants. We have developed an innovative grit blasting process using Biphasic Calcium Phosphate, a Resorbable Biocompatible Blast Media (RBBM). PEEK is biocompatible but an inert material, involving no direct bone bonding. Implants coming from a rabbit experimental study, were processed for X-rays Micro tomography. Light microscopy and SEM were performed.It was demonstrated in this study that the surface treatment on PEEK improve the quality of bone architecture in direct contact with the sample surface, compared to the classical surface of PEEK. These data demonstrate that PEEK rough surface obtained by RBBM blasting maintain high biocompatibility and bone osteoconduction, and promote higher stability of the implant.

Abstract: Surface roughness modulates the osseointegration of orthopaedic and dental titanium implants. High surface roughness is currently obtained by blasting of titanium implants with silica or aluminium abrasive particles. This process includes into the surface abrasive particles and may cause the release of cytotoxic silica or aluminium ions in the peri implant tissue. To overcome this drawback, we currently develop an innovative gridblasting process using Biphasic Calcium Phosphate (BCP) particles (RBBM Resorbable and Biocompatible Blast Media) to generate biocompatible roughened titanium surface. This work present the technique of blasting using RBBM particles to provide a roughened surface which does not release cytotoxic elements and (ii) to assess the effects of such a roughened surface for bone osteointegration in critical size rabbit defect. Our results demonstrate that resorbable biphasic calcium phosphate abrasive particles can be used to create titanium surface roughness. This grid blasting process increases surface roughness of titanium implants and offers a non cytotoxic surface for rapid and efficient osteointegration.