Paper Titles
Mesenchymal Stem Cell Proliferation and Morphological Analysis on Interconnected Macroporous Structures
p.1129
A New Four-Point Bending System to Supply Cultured Adhensive Cells In Vitro with Cyclic Uniaxial Strain
p.1133
Can Basic Fibroblast Growth Factor Pre-Treatment Enhance Mesenchymal Stem Cell Therapy in Undecorticated Posterior Spinal Fusion?
p.1137
Distribution of Seeded Mesenchymal Stem Cells on Hydroxyapatite Porous Ceramics
p.1141
Study on the Chondrogenesis In Vivo of Bone Marrow Stromal Cells Compounded with Alginate Gel
p.1145
Mesenchymal Stem Cell Derived Osteogenic Cells Is Superior to Bone Marrow Aspirate Impregnated Biomaterial Complex in Posterior Spinal Fusion
p.1149
In vitro Investigation of Mesenchymal Stem Cells with Nanophase PLGA/HA Composite
p.1153
In Vivo Osteogenic Potential of Mesenchymal Stromal Cells Derived from Patient''s Bone Marrow on Hydroxyapatite Ceramics
p.1157
Cell Repopulation in Calcium Phosphate Hybridized Tendon Graft
p.1161

Study on the Chondrogenesis In Vivo of Bone Marrow Stromal Cells Compounded with Alginate Gel

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Abstract:

The cartilage tissue engineering is an inspiring and profitable way for the reconstruction of cartilage defects, but it has been hampered by two large obstacles: how to get qualified seed cells and credible scaffold. This study aimed to evaluate the chondrogenic potential of rat bone marrow stromal cells (BMSCs) by loading them on alginate gel. In this study, the compounds of SD rat BMSCs and alginate gel were injected on the dorsum of rats subcutaneously. The implantations were harvested and examined by histological and immunohistochemical examination, in situ hybridization and transmission electron microscopy at different time points after the operations. The results showed that the compounds of BMSCs and alginate gel are promising for cartilage tissue engineering applications.

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Periodical:

Key Engineering Materials (Volumes 330-332)

Pages:

1145-1148

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.330-332.1145

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Online since:

February 2007

Authors:

Lei Liu, Run Liang Chen, Cai Li, Wei Dong Tian, Sheng Wei Li

Keywords:

Alginate, Bone Marrow Stromal Cell, Chondrogenesis

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© 2007 Trans Tech Publications Ltd. All Rights Reserved

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