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Mechanical Properties and Antithrombogenecity of Blend Membrane of Silk Fibroin

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Abstract:

The silk fibroin blend membranes were prepared by adding a small amount of poly (vinyl alcohol) (PVA) and heparin. By controlling the preparation conditions, the tensile strength and elongation at break reached to 8.86 MPa and 231.8%, respectively. Meanwhile the in vitro antithrombogenecity significant increased. The clot times (APTT, TT and PT) all exceeded the measurement limit of clot detection instrument. It is expectable using these natural materials to prepare small caliber vessel.

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Advanced Biomaterials VI View Preview

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Periodical:

Key Engineering Materials (Volumes 288-289)

Pages:

445-448

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.288-289.445

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Online since:

June 2005

Authors:

Yin Tang, Chuanbao Cao, Xilan Ma, Jing Hua Li, He Sun Zhu

Keywords:

Clot Time, Heparin, Mechanical Property, Poly(vinyl alcohol), Silk Fibroin

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© 2005 Trans Tech Publications Ltd. All Rights Reserved

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