The Synthesis and Characteristic of PAA-Ch/SiO2 Hydrogel Nanocomposites by Radiation Methods for Bone Materials

Article Preview

Abstract:

Generally, hydrogel compounds derived from either natural or synthetic chemical suffer from lack of mechanical strength. So high strength poly(acrylic acid) -chitosan-silica (PAA-Ch-Si) hydrogels were prepared by UV light or γ-ray irradiation method for scaffold material application in this paper. The absorption peaks from FTIR show the evidence for the successful grafting of PAA- Ch-Si hydrogel material through radiation co-polymerization. The mechanical property analysis indicate that the maximum compressive strength of this hydrogel was significantly increased to ~42 MPa when PAA incorporated with both chitosan and nano-silica. And from the test results, we can observe that these nanocomposites are fitted to appling for biomedical materials.

You might also be interested in these eBooks

Info:

Periodical:

Pages:

288-291

Citation:

Online since:

December 2012

Export:

Price:

Permissions CCC:

Permissions PLS:

Сopyright:

© 2013 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

[1] Murugan and S. Ramakrishna, Development of nanocomposites for bone grafting, Composites Science and Technology, 65 (2005) p.2385–2406.

DOI: 10.1016/j.compscitech.2005.07.022

Google Scholar

[2] In Yong Kim, Seog Jin Seo, Hyun Seuk Moon, Mi Kyong Yoo, In Young Park, Bom Chol Kim, Chong Su Cho, Chitosan and its derivatives for tissue engineering applications, Biotechnology Advances, 26 (2008) pp.1-21.

DOI: 10.1016/j.biotechadv.2007.07.009

Google Scholar

[3] R. Cortesini Stem cells, Tissue engineering and organogenesis in transplantation, Transpl Immunol, 15 (2005) pp.81-89.

Google Scholar

[4] JM Williams, A. Adewunmi, RM Schek, CL Flanagan, PH Krebsbach, SE Feinberg, Bone tissue engineering using olycarprolactone prolactone scaffold fabricated via selective laser sintering, Biomaterials, 26 (2005) pp.4817-27.

DOI: 10.1016/j.biomaterials.2004.11.057

Google Scholar