Efficient Synthesis of 3,4-Dihydropyrimidin-2(1H)-Ketone Using SbCl3 as Catalyst under Ultrasonic Conditions

Jin Lin; Jing Fen Li; Bin Bin Zheng; Xiao Ting Dai; Jia Feng; Ting Ting Yu

doi:10.4028/www.scientific.net/AMM.316-317.1045

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HomeApplied Mechanics and MaterialsApplied Mechanics and Materials Vols. 316-317Efficient Synthesis of...

Efficient Synthesis of 3,4-Dihydropyrimidin-2(1H)-Ketone Using SbCl₃ as Catalyst under Ultrasonic Conditions

Abstract:

In this study, SbCl₃ as catalyst to benzaldehyde, ethyl acetoacetate and urea as raw material in the ultrasonic radiation synthesis of 3,4-Dihydropyrimidin-2(1H)-ketone. According to the orthogonal design optimization experiment, optimization method ultrasonic extraction technology, and ultimate pass to get the best synthetic condition for: material ratio 1.0,1.0,1.5(mol), ultrasonic power 100 w, ultrasonic time 2 hours, ultrasonic temperature 65°C, the yield is 61.08%.

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Periodical:

Applied Mechanics and Materials (Volumes 316-317)

Pages:

1045-1048

DOI:

https://doi.org/10.4028/www.scientific.net/AMM.316-317.1045

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Online since:

April 2013

Authors:

Jin Lin, Jing Fen Li, Bin Bin Zheng, Xiao Ting Dai, Jia Feng, Ting Ting Yu

Keywords:

3,4-Dihydropyrimidin-2(1H)-Ketone, Oxalic Acid, Ultrasonic

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References

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