A Review: Effect of Sintering Method on the Decomposition of Hydroxyapatite and Density of Hydroxyapatite Zirconia Composites

Abstract:

Hydroxyapatite (HA) is a biomaterial with excellent biocompatibility. However, the brittleness and low fracture toughness of HA have limited its biomedical applications. As such, HA has been incorporated with zirconia (ZrO2) to enhance its mechanical strength. However, ZrO2 addition decreases the phase stability of HA. HA decomposition is not favored because it decreases the mechanical strength of HA/ZrO2. In this paper, the effect of sintering on HA decomposition is reviewed. Experimental results show that hot isostatic pressing of HA/ZrO2 is one of the most effective methods to suppress HA decomposition, yielding the highest relative density compared with other sintering methods.

• Periodical: Applied Mechanics and Materials (Volumes 465-466)
• Pages: 843-846
• DOI: https://doi.org/10.4028/www.scientific.net/AMM.465-466.843
• Online since: December 2013
• Authors: Chee Huan Leong, Andanastuti Muchtar, C.Y. Tan, Masfueh Razali
• Keywords: Biomedical Applications, HA Decomposition, Hydroxyapatite (HA), Sintering Method, Zirconia

References

[1] W. J. O'Brien, Dental Materials and Their Selection, Quintessence Publishing Co, Inc., (2009).

[2] S. Ramesh, C.Y. Tan, S.B. Bhaduri, W.D. Teng, Rapid densification of nanocrystalline hydroxyapatite for biomedical applications, Ceram. Int. 33(7) (2007) 1363-1367.

DOI: 10.1016/j.ceramint.2006.05.009

[3] S. Ramesh, C.Y. Tan, R. Tolouei, M. Amiriyan, J. Purbolaksono, I. Sopyan, W.D. Teng, Sintering behavior of hydroxyapatite prepared from different routes, Mater. & Des. 34(0) (2012) 148-154.

DOI: 10.1016/j.matdes.2011.08.011

[4] B. Nasiri-Tabrizi, A. Fahami, R. Ebrahimi-Kahrizsangi, Effect of milling parameters on the formation of nanocrystalline hydroxyapatite using different raw materials, Ceram. Int. 39(5) (2013) 5751-5763.

DOI: 10.1016/j.ceramint.2012.12.093

[5] W. Siswomihardjo, S. Sunarintyas, A.E. Tontowi, The Effect of Zirconia in Hydroxyapatite on Staphylococcus epidermidis Growth, Int. J. of Biomater. (2012) 4.

DOI: 10.1155/2012/432372

[6] S. Ramesh, C.Y. Tan, I. Sopyan, M. Hamdi, W.D. Teng, Consolidation of nanocrystalline hydroxyapatite powder. Sci. and Tech. of Ad. Mater., Sci. and Tech. of Ad. Mater. 8(1–2) (2007) 124-130.

DOI: 10.1016/j.stam.2006.11.002

[7] V.V. Silva, F.S. Lameiras, Synthesis and characterization of composite powders of partially stabilized zirconia and hydroxyapatite, Mater. Characterization. 45(1) (2000) 51-59.

DOI: 10.1016/s1044-5803(00)00048-6

[8] M.A.F. Afzal, P. Kesarwani, K.M. Reddy, S. Kalmodia, B. Basu, K. Balani, Functionally graded hydroxyapatite-alumina-zirconia biocomposite: Synergy of toughness and biocompatibility, Mater. Sci. and Eng.: C. 32(5) (2012) 1164-1173.

DOI: 10.1016/j.msec.2012.03.003

[9] X. Miao, Y. Chen, H. Guo, K.A. Khor, Spark plasma sintered hydroxyapatite-yttria stabilized zirconia composites, Ceram. Int. 30(7) (2004) 1793-1796.

DOI: 10.1016/j.ceramint.2003.12.117

[10] Z. Evis, M. Usta, I. Kutbay, Improvement in sinterability and phase stability of hydroxyapatite and partially stabilized zirconia composites, J Eur Ceram Soc. 29(4) (2009) 8-8.

DOI: 10.1016/j.jeurceramsoc.2008.07.020

[11] A. Rapacz-Kmita, A. Slosarczyk, Z. Paszkiewicz, C. Paluszkiewicz, Phase stability of hydroxyapatite–zirconia (HAp–ZrO2) composites for bone replacement, J. of Mol. Struc. 704(1–3) (2004) 333-340.

DOI: 10.1016/j.molstruc.2004.02.047

[12] P. Parente, B. Savoini, B. Ferrari, M.A. Monge, R. Pareja, A.J. Sanchez-Herencia, Effect of highly dispersed yttria addition on thermal stability of hydroxyapatite, Mater. Sci. and Eng. 33(2) (2013) 864-869.

DOI: 10.1016/j.msec.2012.11.013

[13] C.J. Liao, F.H. Lin, K.S. Chen, J.S. Sun, Thermal decomposition and reconstitution of hydroxyapatite in air atmosphere, J. Biomater. 20(19) (1999) 1807-1813.

DOI: 10.1016/s0142-9612(99)00076-9

[14] D. Curran, T. Fleming, M. Towler, S. Hampshire, Mechanical properties of hydroxyapatite–zirconia compacts sintered by two different sintering methods, J. Mater Sci: Mater Med. 21(4) (2010) 1109-1120.

DOI: 10.1007/s10856-009-3974-z

[15] C.Y. Chiu, H.C. Hsu, W.H. Tuan, Effect of zirconia addition on the microstructural evolution of porous hydroxyapatite, Ceram. Int. 33(5) (2007) 715-718.

DOI: 10.1016/j.ceramint.2005.12.008

[16] K.A. Khalil, S.W. Kim, H.Y. Kim, Consolidation and mechanical properties of nanostructured hydroxyapatite–(ZrO2 + 3mol% Y2O3) bioceramics by high-frequency induction heat sintering, Mater. Sci. & Eng. 456(1–2) (2007) 368-372.

DOI: 10.1016/j.msea.2006.12.005

[17] S. Ramesh, K.L. Aw, R. Tolouei, M. Amiriyan, C.Y. Tan, M. Hamdi, J. Purbolaksono, M.A. Hassan, W.D. Teng, Sintering properties of hydroxyapatite powders prepared using different methods, Ceram. Int. 39(1) (2013) 111-119.

DOI: 10.1016/j.ceramint.2012.05.103

[18] M.R. Towler, I.R. Gibson, The effect of low levels of zirconia addition on the mechanical properties of hydroxyapatite, J. of Mater. Sci. Letters. 20(18) (2001) 1719-1722.

[19] M. Mazaheri, M. Haghighatzadeh, A.M. Zahedi, S.K. Sadrnezhaad, Effect of a novel sintering process on mechanical properties of hydroxyapatite ceramics, J. of Alloys and Compounds. 471(1–2) (2009) 180-184.

DOI: 10.1016/j.jallcom.2008.03.066

[20] C. Ergun, Enhanced phase stability in hydroxylapatite/zirconia composites with hot isostatic pressing, Ceram. Int. 37(3) (2011) 935-942.

DOI: 10.1016/j.ceramint.2010.11.001

[21] M.D. McNeese, D.C. Lagoudas, T.C. Pollock, Processing of TiNi from elemental powders by hot isostatic pressing, Mater. Sci. & Eng. 280(2) (2000) 334-348.

DOI: 10.1016/s0921-5093(99)00550-x

[22] R.A. Donald, P. P Pradeep, The Science and Engineering of Materials, Thomsom Learning, Singapore, (2006).

[23] G.E. Gazza, R.N. Katz, Densification of Ceramics by Gas Overpressure Sintering, MRS Online Proceedings Library (1991) 251.

DOI: 10.1557/proc-251-199