Highly-Efficient Preparation of Key Intermediate of Huperzine A

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Abstract:

Huperzine A was approved for curing Alzheimers disease in the early 1990s in China. We explored a highly-efficient synthetic route for the key intermediate in the total synthesis of this natural product. Only common reagents and conditions were involved. So our new route has potential application in large-scale preparation of the key intermediate.

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157-160

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January 2014

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© 2014 Trans Tech Publications Ltd. All Rights Reserved

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