Development and Validation of a Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS) Method for the Determination of Dimethomorph and Tebuconazole Residue in Soil

Abstract:

A liquid chromatographic-tandem mass spectrometric (LC-MS/MS) method for the simultaneous quantification and identification of dimethomorph and tebuconazole in soil has been developed and validated. The samples were pre-concentrated and purified using QuEChERS method extraction,which provided satisfactory results. The separation was performed on a Waters ACQUITY UPLC C18 column with a linear gradient of acetonitrile - water containing 5 mM ammonium acetate. The optimised method offered a good linear correlation (r² > 0.99), excellent precision (RSD < 4.0%) and preferable recovery (from 82% to 102%). The limits of detection (LOD) of dimethomorph and tebuconazole were 0.004mg/kg and 0.003 mg/kg, respectively. The validated method was successfully applied to the rapid screening for the two pesticides in soil..

• Periodical: Applied Mechanics and Materials (Volumes 522-524)
• Pages: 132-135
• DOI: https://doi.org/10.4028/www.scientific.net/AMM.522-524.132
• Online since: February 2014
• Authors: Dai Zhu Lv, Zhu Zhu, Hong Qiu Yuan, Jin Hui Luo*
• Keywords: Liquid Chromatography-Tandem Mass Spectrometry, Pesticides, Residues, Soil

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