A Portable Electroencephalogram Recording System for Rats

Abstract:

A wireless portable electroencephalogram (EEG) recording system for animals was designed, manufactured and then tested in rats. The system basically consisted of four modules: 1) EEG collecting module with the wireless transmitter and receiver (designed by NRF24LE1), 2) filter bank consisting of pre-amplifier, band pass filter and 50Hz trapper, 3) power management module and 4) display interface for showing EEG signals. The EEG data were modulated firstly and emitted by the wireless transmitter after being amplified and filtered. The receiver demodulated and displayed the signals in voltage through serial port. The system was designed as surface mount devices (SMD) with small size (20mm×25mm×3mm) and light weight (4g), and was fabricated of electronic components that were commercially available. The test results indicated that in given environment the system could stably record more than 8 hours and transmit EEG signals over a distance of 20m. Our system showed the features of small size, low power consumption and high accuracy which were suitable for EEG telemetry in rats.

• Periodical: Applied Mechanics and Materials (Volume 577)
• Pages: 1236-1240
• DOI: https://doi.org/10.4028/www.scientific.net/AMM.577.1236
• Online since: July 2014
• Authors: Dian Zhang*, Bo Wang, Qing Liang Qin
• Keywords: Brain Computer Interface (BCI), Electroencephalogram (EEG), Filter Bank

References

[1] Jr. JB. Ranck. Which elements are excited in electrical stimulation of mammalian central nervous system: a review. Brain Res. Vol. 98 (1975), p.417.

DOI: 10.1016/0006-8993(75)90364-9

[2] E.J. Tehovnik. Electrical stimulation of neural tissue to evoke behavioral responses. Journal of Neuroscience Methods. Vol. 65 (1996), p.1.

DOI: 10.1016/0165-0270(95)00131-x

[3] A.A. Fenton and RU. Muller. Using digital video techniques to identify correlations between behavior and the activity of single neurons. Journal of Neuroscience Methods, Vol 70 (1996), p.211.

DOI: 10.1016/s0165-0270(96)00082-9

[4] I. Obeid, M.A.L. Nicolelis and P. D . Wolf. A multichannel telemetry system for single unit neural recordings. Journal of Neuroscience Methods, vol. 133 (2004), p.33.

DOI: 10.1016/j.jneumeth.2003.09.023

[5] J.X. Cai and W.Z. Zhang. Bio-electronics, volume 5 of Progress in Sensor technology and its application, chapter, 5, Peking University Press (1997).

[6] O. Michio. in: OP amplifier design, edited by L. Wang, volume 3 of Progress in eliminate bias, chapter, 2, Science Press (2004).

[7] M. Lou, C.C. Eschenfelder and T. Herdngen. Therapeutic window for use of hyperbaric oxygenation in focal transient ischemia in rats. Stroke, vol. 35(2004), p.578.

DOI: 10.1161/01.str.0000111599.77426.a0

[8] G. Paxinos and C. Waston, Stereotaxic Atlas of the rat, edited by Q.X. Zhuge, 3rd, People's Medical Publishing House (2005).

[9] J.K. Chapin, K.A. Moxon and R.S. Markowitz. Real time control of a robot arm using simultaneously recorded neurons in the motor cortex. Nature Neuroscience, vol. 2(1999), p.664.

DOI: 10.1038/10223

[10] D. HAN and G.L. ZHANG. Abnormal EEG waves and its physics characteristics of penicillin-induced epilepsy model in rats. Chinese Journal of Medical Physics. vol. 15(1998), p.85.