Synthesis and Characterization of a New Coumarin-1,2,3-Triazole Diad

Abstract:

A new coumarin-1,2,3-triazole diad was designed and synthesized by Pechmann-Duisberg reaction and click chemistry. The three-step synthetic route to the target compound afforded an overall yield of 56%. The structures of the synthesized compounds were characterized by ¹H NMR, ¹³C NMR, IR and mass spectrum. The click chemistry provided an ideal approach for synthesis under mild conditions of coumarin-1,2,3-triazole diads which may exhibit excellent biological activities such as antitubercular activity.

• Periodical: Applied Mechanics and Materials (Volume 618)
• Pages: 170-174
• DOI: https://doi.org/10.4028/www.scientific.net/AMM.618.170
• Online since: August 2014
• Authors: Hong Qi Li*, Xiu Juan Tian, Zhen Chen, Ding Xiao, Ning Fang, Yan Xiang Lv, Liang Gu
• Keywords: 3-Triazole, Click Chemistry, Coumarin, Synthesis

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