Development of UV LED Hydrogel Formulation Based on Polyacrylamide Hydrogel

Abstract:

Recent trends show that the UV LED light source can greatly reduce environmental effect without compromising performance as compared to conventional UV mercury-based lamp (UV Hg) system. In this study, the possibility of using UV LED technology for photopolymerization of polyacrylamide (PAAm) hydrogels is presented. This has strongly drives the needs for suitable water-soluble photoinitiator formulation. Specifically, the photoinitiator must possess characteristic wavelength within UV LED range as UV LED emits monochromatic light sources only (365 nm or 385 nm). Here, the commercially available photoinitiator Oligo [2-hydroxy-2-methyl-1-[4-(1-methylvinyl) phenyl] propanone] (Chivacure 300) was chosen. However, Chivacure 300 has limited solubility in water. Hence, addition of tetrahydrofuran (THF) at various ratios was required. The results demonstrated that 9.5:0.5 ratio of water/THF was the minimum ratio needed for the solubility of Chivacure 300. After the synthesis of PAAm hydrogels, almost complete conversion of hydrogels was achieved (> 80 %). The highest conversion was achieved with formulation of Chivacure 300 in 9.5:0.5 ratio of water/THF. At this ratio, the hydrogels obtained were transparent. With increasing ratio of THF in water, the appearance of hydrogels gradually changed to cloudy. Indeed, UV LED technology can be used to polymerize PAAm hydrogels with comparably high conversion to conventional UV Hg system.

• Periodical: Applied Mechanics and Materials (Volume 695)
• Pages: 102-105
• DOI: https://doi.org/10.4028/www.scientific.net/AMM.695.102
• Online since: November 2014
• Authors: Nur Farizah Ayub, Shahrir Hashim, Nadia Adrus*
• Keywords: Chivacure 300, Hydrogel, Polyacrylamide (PAAm), Uv LED

References

[1] Q. Yang, N. Adrus, F. Tomicki, and M. Ulbricht, Composites of Functional Polymeric Hydrogels and Porous Membranes, J. Mater. Chem. 21: (2011) 2783-2811.

DOI: 10.1039/c0jm02234a

[2] N.A. Peppas and A.R. Khare, Preparation, Structure and Diffusional Behavior of Hydrogels in Controlled Release, Adv. Drug Delivery Rev. 11: (1993) 1-35.

DOI: 10.1016/0169-409x(93)90025-y

[3] C. Santulli, Mechanical Charecterisation of N-Isopropylacrylamide (NIPA) Gels for Use in Smart Actuators, M. P. J. 6(1): (2011) 39-50.

[4] O. Okay and W. Oppermann, Polyacrylamide-Clay Nanocomposite Hydrogels: Rheological and Light Scattering Characterization, Macromolecules. 40: ( 2007) 3378-3387.

DOI: 10.1021/ma062929v

[5] N. Adrus and M. Ulbricht, Rheological Studies on PNIPAAm Hydrogel Synthesis via in Situ Polymerization and on Resulting Viscoelastic Properties, React. Func. Polym. 73: (2013) 141-148.

DOI: 10.1016/j.reactfunctpolym.2012.08.015

[6] K.T. Nguyen and J.L. West, Photopolymerizable Hydrogels for Tissue Engineering Applications, Biomaterials. 23: (2002) 4307-4314.

DOI: 10.1016/s0142-9612(02)00175-8

[7] M. Kurecic, M.S. Smole, and K.S. Kleinschek, UV Polymerization of Poly (N-Isopropylacrylamide) Hydrogel, J. Mater. Technol. 46(1): (2012) 87-91.

[8] Lilian C. Lopergolo, A.B. Lugao, and L.H. Catalani, Direct UV Photocrosslinking of Poly(N-Vinyl-2-Pyrrolidone) (PVP) to Produce Hydrogels, Polymer. 44: (2003) 6217-6222.

DOI: 10.1016/s0032-3861(03)00686-4

[9] L.M. Geever, D.M. Devine, M.J.D. Nugent, J.E. Kennedy, J.G. Lyons, A. Hanley, and C.L. Higginbotham, Lower Critical Solution Temperature Control and Swelling Behaviour of Physically Crosslinked Thermosensitive Copolymers Based on N-Isopropylacrylamide, Eur. Polym. J. 42: (2006).

DOI: 10.1016/j.eurpolymj.2006.06.002

[10] M.R.P. Karsten, UV LED Curing for Wood Coatings. Available from: http: /www. phoseon. com/Documentation/uv-led-curing-for-wood-coatings. pdf.

DOI: 10.3390/coatings5041019

[11] K. Ikemura and T. Endo, A Review of The Development of Radical Photopolymerization Initiators Used for Designing Light-Curing Dental Adhesives and Resin Composites, J. Dent. Mater. 29(5): (2010) 481-501.

DOI: 10.4012/dmj.2009-137

[12] X. -Z. Zhang and C. -C. Chu, Preparation of Thermosensitive PNIPAAm Hydrogels with Superfast Response, Chem. Commun. (2004) 350-351.

DOI: 10.1039/b313073h

[13] A.Y. Kwok, G.G. Qiao, and D.H. Solomon, Synthetic Hydrogels. 1. Effects of Solvent on Poly(Acrylamide) Networks, Polymer. 44(20): (2003) 6195-6203.

DOI: 10.1016/s0032-3861(03)00671-2

[14] X.S. Wu, A.S. Hoffman, and P. Yager, Synthesis and Characterization of Thermally Reversible Macroporous Poly (N-lsopropylacrylamide) Hydrogels, J. Polym. Sci. A: Polym. Chem. 30: (1992) 2121-2129.

DOI: 10.1002/pola.1992.080301005