Titania Nanotube Arrays Load with Ibuprofen by Solvothermal and its Release Behavior

Zhang Wang; Ping Li; Fei Luo; Dan Mao; Xiu Feng Xiao

doi:10.4028/www.scientific.net/AMR.1030-1032.2368

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HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 1030-1032Titania Nanotube Arrays Load with Ibuprofen by...

Titania Nanotube Arrays Load with Ibuprofen by Solvothermal and its Release Behavior

Abstract:

In this study, the vertically aligned titania nanotube arrays (TNTs) was fabricated on the surface of titanium substrate in fluoride-containing electrolytes via self-ordering electrochemical anodization. The prepared TNTs loaded with ibuprofen (IBU) by solvothermal to achieve a local drug delivery system and its release properties were investigated. The samples were characterized by field emission scanning electronic microscope (FE-SEM), X-ray diffraction (XRD), Fourier transform infrared (FT-IR). The results indicated that the IBU drug molecules were successfully loaded on the surface of TNTs and the drug release shows a sustained release process. It suggested that TNTs as drug carrier had the properties of sustained release which have a good application prospect in biomedical field.

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Periodical:

Advanced Materials Research (Volumes 1030-1032)

Pages:

2368-2371

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.1030-1032.2368

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Online since:

September 2014

Authors:

Zhang Wang, Ping Li, Fei Luo, Dan Mao, Xiu Feng Xiao*

Keywords:

Drug Delivery System, Ibuprofen, Solvothermal, Titania Nanotube

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* - Corresponding Author

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