Investigation of Genotoxicity of Gold Nanoparticles Prepared by the Electric Spark Dispersion Method

Evgenii Plotnikov; Sergey P. Zhuravkov; Andrew Gapeyev; Vladimir Plotnikov; Dmitry Martemiyanov

doi:10.4028/www.scientific.net/AMR.1040.65

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HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 1040Investigation of Genotoxicity of Gold...

Investigation of Genotoxicity of Gold Nanoparticles Prepared by the Electric Spark Dispersion Method

Abstract:

The paper presents the results of investigations of genotoxicity and morphological characteristics of nanoscale gold particles prepared by the electric spark dispersion method in a water medium. To investigate the properties we used comet assay, transmission electron microscopy, thermal desorption of nitrogen (BET). It was revealed, gold particles did not cause DNA damage at low concentrations (0.01 - 0.1 mg/ml) and detectable level of genotoxicity of gold nanoparticles is observed at concentrations of 0.3 mg/ml and above.

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Periodical:

Advanced Materials Research (Volume 1040)

Pages:

65-69

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.1040.65

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Online since:

September 2014

Authors:

Evgenii Plotnikov*, Sergey P. Zhuravkov, Andrew Gapeyev, Vladimir Plotnikov, Dmitry Martemiyanov

Keywords:

Electric Spark Dispersion, Genotoxicity, Gold Nanoparticles

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