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Synthesis of 5-(4-nitrophenyl)-2-aminopyrazine
Abstract:
5-(4-nitrophenyl)-2-aminopyrazine (13) was synthesized from 2-aminopyrazine (9) through two steps including monobrominated reaction, Suzuki-Miyaura coupling and the structures were confirmed by 1H NMR and MS spectrum. The synthetic method of 13 was optimized and can be used to synthesize 5-(4-nitrophenyl)-2-aminopyrazine derivatives.
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67-70
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Online since:
December 2014
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© 2015 Trans Tech Publications Ltd. All Rights Reserved
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