Optimization of Preparing Technology of Magnetic Carboxymethylchitosan Microspheres Molecular-Imprinted by 6-ethoxydihydrosanguinarine Using Response Surface Methodology

Ming Zhong; Rui Qing Long

doi:10.4028/www.scientific.net/AMR.1090.142

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HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 1090Optimization of Preparing Technology of Magnetic...

Optimization of Preparing Technology of Magnetic Carboxymethylchitosan Microspheres Molecular-Imprinted by 6-ethoxydihydrosanguinarine Using Response Surface Methodology

Abstract:

In the present study, the response surface methodology (RSM) based on central composite design (CCD) was employed to optimize the preparation process of magnetic carboxymethylchitosan microspheres molecular-imprinted by 6-ethoxydihydrosanguinarine. The optimum parameters were as follows: CMCS concentration,3.24% ;CMCS/EtOSA ratio, 37.79 (g/g) and oil/water ratio, 2.76 (v/v).The adsorption rate from the optimized model was 39.34 (mg/g). Under the optimized conditions, the adsorption rate for the verifying experiments was well matches with the predicted value.

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Periodical:

Advanced Materials Research (Volume 1090)

Pages:

142-147

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.1090.142

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Online since:

February 2015

Authors:

Ming Zhong*, Rui Qing Long

Keywords:

Magnetic Microspheres, Molecularly Imprinting Technique, Response Surface Methodology

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