Inclusion Process of Curcuminoid-β-Cyclodextrin Complex and its Stability

Abstract:

Curcuminoid is an important natural product, but it is water insoluble, and sensitive to light, pH, solvent system, and oxygen.The inclusion process of curcuminoid-β-CD complex was investigated by the orthogonal experiment, and the stability of curcuminoid-β-CD complex was studied under different conditions. The results show that the encapsulation rate is 87.34% under optimized conditions of temperature 50 , time 1.5 h and material ratio 1:30(wcurcuminoid : wβ-CD). The stability of curcuminoid-β-cyclodextrin complex increases compared to curcuminoid. Therefore, the complex formation of curcuminoid with β-CD is an effective method to improve the stability of curcuminoid.

• Periodical: Advanced Materials Research (Volumes 152-153)
• Pages: 1487-1491
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.152-153.1487
• Online since: October 2010
• Authors: Xiang Zhou Li, Chun Tao Kuang, Jun Jun Yang, Yuan Liang Guo, Yan Hong Yang
• Keywords: Curcuminoid, Inclusion Process, Stability, β-Cyclodextrin

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