Influence of Metal Cations on the Structure and Release Property of Layered Double Hydroxide-Ibuprofen Host-Guest Materials

Article Preview

Abstract:

Layered double hydroxide (LDH)-ibuprofen (IBU) host-guest materials were prepared by in situ coprecipitation method for the purpose of drug controlled release. Three hosts containing different metal cations, MgAl-, ZnAl-, and MgFe-LDH, were studied. The results showed that the types of the metal cations had great influence on the structures of the host-guest materials and thus led to different drug release properities.

You might also be interested in these eBooks

Info:

Periodical:

Advanced Materials Research (Volumes 152-153)

Pages:

556-559

Citation:

Online since:

October 2010

Export:

Price:

Permissions CCC:

Permissions PLS:

Сopyright:

© 2011 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

[1] K. Ladewig, Z.P. Xu and G.Q.M. Lu: Expert Opin. Drug Deliv. Vol. 6 (2009), p.907.

Google Scholar

[2] P. Gunawan and R. Xu: J. Pharm. Sci. Vol. 97 (2008), p.4367.

Google Scholar

[3] Z. Gu, A.C. Thomas, Z.P. Xu: Chem. Mater. Vol. 20 (2008), p.3715.

Google Scholar

[4] M. Trikeriotis and D.F. Ghanotakis: Int. J. Pharm. Vol. 332 (2007), p.176.

Google Scholar

[5] J.H. Yang, Y.S. Han, M. Park: Chem. Mater. Vol. 19 (2007), p.2679.

Google Scholar

[6] V. Ambrogi, G. Fardella, G. Grandolini: Int. J. Pharm. Vol. 220 (2001), p.23.

Google Scholar

[7] J.M. Oh, T.T. Biswick and J.H. Choy: J. Mater. Chem. Vol. 19 (2009), p.2553.

Google Scholar

[8] P.J. Sideris, U.G. Nielsen, Z.H. Gan: Science Vol. 321 (2008), p.113.

Google Scholar

[9] U. Costantino, M. Nocchetti, M. Sisani: Z. Kristallogr. Vol. 224 (2009), p.273.

Google Scholar

[10] C.R. Gordijo, C.A.S. Barbosa, A. Ferreira: J. Pharm. Sci. Vol. 94 (2005), p.1135.

Google Scholar

[11] F. Leroux and C. Taviot-Gueho: J. Mater. Chem. Vol. 15 (2005), p.3628.

Google Scholar

[12] H. Nakayama, N. wasa and M. Tsuhako: Int. J. Pharm. Vol. 269 (2004), p.469.

Google Scholar

[13] X. Zhang, H. Zhang, M. Wei: Chem. J. Chin. Univ. Vol. 25 (2004), p.1869.

Google Scholar

[14] M.R. Berber, K. Minagawa, M. Katoh: Eur. J. Pharm. Sci. Vol. 35 (2008), p.354.

Google Scholar