Eccentric loading experiment of 13 steel tube-reinforced concrete columns and a reinforced concrete column is implemented. The whole process from the start load on the steel tube-reinforced concrete column until damage has been researched. Change of ultimate bearing capacity with eccentricity, longitudinal reinforcement ratio, position coefficient has been studied, and deflection curve and load-vertical displacement curve under eccentric compressive load were obtained. Failure characteristics of steel tube-reinforced concrete were divided into two different type, small eccentric damage and big eccentric damage. With the same conditions, when steel tube ratio of steel tube-reinforced concrete was 2%, its ultimate bearing capacity was nearly double of reinforced concrete columns.