Pressure bump is a serious disaster to threat coal mine production safety. The roof and floor strata in Kailuan coal mine are made of sandstone and mudstone with relatively poor rigidity. Most of mines have been into the deep mining stage over one thousand meters. High-stress becomes the key factor induced pressure bump. In this paper, according to coal mining strata, fault development, mine inflow and other geological factors, based on fracturing parameters of mine rock and wall rock in the pilot mines (Qianjiaying Mine, Tangshan Coal Mine), boundary conditions of the occurrence of pressure bump is tested by numerical simulation using RFPA software. It discusses the mechanism and laws of pressure bump under high stress in the deep mining. Mining face and roadway are taken real-time monitoring, using micro seismic monitoring system (MMS). The location and level of micro seismic events within the coal formation caused by breakdown could achieve precise position. Spatial distribution and characteristics of coal and rock bursting could be identified. The stability of coal and rock could be monitored real-time and analyzed. Pressure bump could be predicted and prevented effectively.